| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA940161 | B | Activation of mouse TRPA1 expressed in CHO cells at 100 uM by calcium imaging FLIPR assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA940162 | B | Binding affinity to mouse TRPA1 expressed in HEK293T cells at 100 uM assessed as covalent protein modification | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA940163 | B | Activation of mouse TRPA1 C415S mutant expressed in CHO cells at 100 uM by calcium imaging FLIPR assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA940164 | B | Activation of mouse TRPA1 C422S mutant expressed in CHO cells at 100 uM by calcium imaging FLIPR assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA940165 | B | Activation of mouse TRPA1 C622S mutant expressed in CHO cells at 100 uM by calcium imaging FLIPR assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA940166 | B | Activation of mouse TRPA1 expressed in CHO cells assessed as increase in intracellular calcium level | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA940167 | B | Activation of mouse TRPA1 expressed in HEK293T cells at 50 uM assessed as activation of cation conductance by electrophysiology | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA940971 | B | Activation of mouse TRPA1 expressed in HEK293T cells at 30 uM assessed as activation of cation conductance by electrophysiology | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA940972 | B | Activation of mouse TRPA1 expressed in HEK293T cells at 100 uM assessed as activation of cation conductance by electrophysiology | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA940973 | B | Reversal of activation of mouse TRPA1 expressed in HEK293T cells at 400 uM in presence of dithiothreitol by electrophysiology | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA940974 | B | Activation of mouse TRPA1 expressed in HEK293T cells at 50 uM in presence of dithiothreitol by electrophysiology | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA1118225 | F | Antagonist activity at mouse TRPA1 channel expressed in CHO cells assessed as inhibition of cinnamaldehyde-induced intracellular calcium influx | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA1118235 | B | Activation of mouse TRPA1 channel | Mus musculus | 3 | single protein format | Scientific Literature | ||
| 14. | ALA1118239 | F | Antagonist activity at mouse TRPA1 channel expressed in CHO cells assessed as blockade of agonist-induced whole cell conductance by electrophysiology | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA1118244 | F | Agonist activity at mouse TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influx | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA1118245 | F | Agonist activity at TRPA1 channel in mouse dorsal root ganglion cells assessed as increase in intracellular calcium influx by radiometric Ca2+ imaging | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 17. | ALA1118249 | F | Agonist activity at mouse TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium influx | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 18. | ALA3299553 | B | Antagonist activity at mouse TRPA1 expressed in CHO-TREX cells assessed as inhibition of cinnamaldehyde-induced calcium flux incubated 10 mins prior to cinnamaldehyde addition by FLIPR assay relative to control | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 19. | ALA3791382 | B | Antagonist activity at mouse TRPA1 natively expressed in human IMR90 cells assessed as inhibition of AITC mediated calcium flux at 0.5 to 50 uM preincubated for 60 mins followed by AITC addition by Fluo-4 NW dye based fluorometric assay in presence of ruthenium dye | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA3791383 | B | Antagonist activity at mouse TRPA1 natively expressed in human IMR90 cells assessed as inhibition of AITC mediated calcium flux at 50 uM preincubated for 60 mins followed by AITC addition by Fluo-4 NW dye based fluorometric assay in presence of ruthenium dye | Mus musculus | 1 | cell-based format | Scientific Literature |
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