# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3767684 | Binding | Displacement of [3H]SCH-23390 from dopamine D1 receptor in rat striatum incubated for 15 mins by liquid scintillation counting analysis | Rattus norvegicus | 13 | ALA3763018 | assay format | Scientific Literature | |
2. | ALA645375 | Functional | Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activity | 9 | ALA1123890 | assay format | Scientific Literature | ||
3. | ALA664614 | Functional | Degradation rate constant for dopamine transporter by D1 receptor in nucleus accumbens was determined | 2 | ALA1136786 | assay format | Scientific Literature | ||
4. | ALA664615 | Functional | Half life of recovery for dopamine transporter by D1 receptor in nucleus accumbens was determined | 2 | ALA1136786 | tissue-based format | Scientific Literature | ||
5. | ALA672898 | Functional | Dopamine receptor D1 agonist efficacy was measured with stimulation of dopamine-sensitive rat adenylate cyclase in caudate membranes. Partial agonist, maximum effect 60% of dopamine maximum effect. | 1 | ALA1123777 | cell membrane format | Scientific Literature | ||
6. | ALA672899 | Functional | Dopamine receptor D1 agonist efficacy was measured with stimulation of dopamine-sensitive rat adenylate cyclase in caudate membranes; NS means not significant. | 1 | ALA1123777 | cell membrane format | Scientific Literature | ||
7. | ALA672900 | Functional | Dopamine receptor D1 agonist efficacy was measured with stimulation of dopamine-sensitive rat adenylate cyclase in caudate membranes; NS means not significant. | 1 | ALA1123777 | cell membrane format | Scientific Literature | ||
8. | ALA672680 | Functional | Effective concentration was determined for the adenylate cyclase activity in rat striatal tissue as a measure of Dopamine receptor D1 functional activity | 12 | ALA1129293 | tissue-based format | Scientific Literature | ||
9. | ALA672681 | Binding | Tested for its ability to stimulate rat caudate adenylate cyclase (Dopamine receptor D1) at 10 uM | 2 | ALA1122865 | single protein format | Scientific Literature | ||
10. | ALA672682 | Binding | Tested for its affinity towards Dopamine receptor D1 in rat striatal membrane | 1 | ALA1127850 | cell membrane format | Scientific Literature | ||
11. | ALA672683 | Functional | The ability of a compound to stimulate dopamine-sensitive rat caudate adenylate cyclase or to antagonise the stimulant of dopamine was used as measure of D1 efficacy | 5 | ALA1123482 | assay format | Scientific Literature | ||
12. | ALA672684 | Functional | Stimulation of dopamine-sensitive rat caudate adenylate cyclase or antagonism of dopamine stimulus as measure of D1 efficacy; No stimulation | Rattus norvegicus | 8 | ALA1123482 | assay format | Scientific Literature | |
13. | ALA672685 | Binding | Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatum | Rattus norvegicus | 10 | ALA1125441 | cell membrane format | Scientific Literature | |
14. | ALA672686 | Binding | Ability to displace [3H]-SCH- 23390 (0.2 nM) from corpus striatum of rat Dopamine receptor D1 | 2 | ALA1145103 | single protein format | Scientific Literature | ||
15. | ALA669070 | Binding | Displacement of [3H]cis-flupenthixol from Dopamine receptor D1 in rat brain | Rattus norvegicus | 2 | ALA1124042 | tissue-based format | Scientific Literature | |
16. | ALA669071 | Binding | Ability to inhibit binding of [3H]-SCH- 23390 to Dopamine receptor D1 in rat striatal membranes | 3 | ALA1125929 | cell membrane format | Scientific Literature | ||
17. | ALA669072 | Binding | Affinity for displacement of [3H]SCH-23390 labeled Dopamine receptor D1 | 1 | ALA1123615 | single protein format | Scientific Literature | ||
18. | ALA669073 | Binding | Affinity for displacement of [3H]SCH-23390 labeled Dopamine receptor D1; ND means no data | 1 | ALA1123615 | single protein format | Scientific Literature | ||
19. | ALA669074 | Binding | Affinity for displacement of [3H]WB-4101 labeled Dopamine receptor D1 | 2 | ALA1123615 | single protein format | Scientific Literature | ||
20. | ALA669075 | Binding | Affinity for displacement of [3H]clonidine labeled Dopamine receptor D1 | 2 | ALA1123615 | single protein format | Scientific Literature |