# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1100876 | B | Inhibition of AFABP-mediated lipolysis in mouse 3T3L1 cells assessed as reduction in non-esterified fatty acid efflux after 24 hrs | Mus musculus | 1 | ALA1154280 | cell-based format | Scientific Literature | |
2. | ALA1100877 | B | Inhibition of AFABP-mediated lipolysis in forskolin-stimulated mouse 3T3L1 cells assessed as reduction in non-esterified fatty acid efflux after 24 hrs | Mus musculus | 1 | ALA1154280 | cell-based format | Scientific Literature | |
3. | ALA3404797 | B | Inhibition of FABP4 in mouse 3T3-L1 cells assessed as reduction of forskolin-induced lipolysis at 50 uM | Mus musculus | 1 | ALA3400075 | cell-based format | Scientific Literature | |
4. | ALA3404798 | B | Inhibition of FABP4 in mouse 3T3-L1 cells assessed as reduction of forskolin-induced lipolysis at 100 uM | Mus musculus | 1 | ALA3400075 | cell-based format | Scientific Literature | |
5. | ALA3828891 | B | Inhibition of FABP4 in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha production after 24 hrs by ELISA | Mus musculus | 3 | ALA3826919 | cell-based format | Scientific Literature | |
6. | ALA3828892 | B | Inhibition of FABP4 in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha expression after 24 hrs by qPCR method | Mus musculus | 3 | ALA3826919 | cell-based format | Scientific Literature | |
7. | ALA3828893 | B | Inhibition of FABP4 in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-6 expression after 24 hrs by qPCR method | Mus musculus | 3 | ALA3826919 | cell-based format | Scientific Literature | |
8. | ALA4271672 | B | Inhibition of FABP4 in mouse 3T3L1 cells assessed as reduction in forskolin-stimulated lipolysis by measuring reduction in glycerol level pretreated for 24 hrs followed by forskolin stimulation and measured after 2 hrs | Mus musculus | 2 | ALA4270520 | cell-based format | Scientific Literature | |
9. | ALA4271673 | B | Inhibition of FABP4 in mouse 3T3L1 pre-adipocytes assessed as increase in triglyceride level at 50 uM treated for 6 days during differentiation period supplemented with fresh medium containing compounds for every 2 days measured post last dose | Mus musculus | 2 | ALA4270520 | cell-based format | Scientific Literature | |
10. | ALA4271674 | B | Inhibition of FABP4 in mouse 3T3L1 pre-adipocytes assessed as increase in lipid accumulation at 50 uM treated for 6 days during differentiation period supplemented with fresh medium containing compounds for every 2 days measured post last dose by Oil red O staining based microscopic analysis | Mus musculus | 2 | ALA4270520 | cell-based format | Scientific Literature | |
11. | ALA4399649 | B | Inhibition of FABP4 in mouse 3T3L1 cells assessed as inhibition of forskolin-stimulated lipolysis at 30 uM preincubated for 24 hrs followed by forskolin addition and measured after 2 hrs | Mus musculus | 4 | ALA4396930 | cell-based format | Scientific Literature | |
12. | ALA4399655 | B | Inhibition of FABP4 in mouse RAW264.7 cells assessed as decrease in LPS-induced NF-kappaB phosphorylation at 30 to 60 uM preincubated for 12 hrs followed by LPS addition and measured after 10 mins by Western blot analysis | Mus musculus | 4 | ALA4396930 | cell-based format | Scientific Literature | |
13. | ALA4399656 | B | Inhibition of FABP4 in mouse RAW264.7 cells assessed as decrease in LPS-induced IKK phosphorylation at 30 to 60 uM preincubated for 12 hrs followed by LPS addition and measured after 10 mins by Western blot analysis | Mus musculus | 4 | ALA4396930 | cell-based format | Scientific Literature | |
14. | ALA4605266 | B | Inhibition of FABP4 in mouse 3T3L1 cells assessed as inhibition of forskolin-stimulated lipolysis by measuring free glycerol at 1 to 25 uM incubated for 24 hrs followed by forskolin stimulation and measured after 2 hrs | Mus musculus | 2 | ALA4602698 | cell-based format | Scientific Literature | |
15. | ALA4742607 | B | Inhibition of fatty acid binding protein 4 in mouse 3T3-L1 cells assessed as reduction in adiponectin expression level at 10 uM dosed during day 2 to 6 and followed by drug replacement every 48 hrs by LC-MS/MS analysis based proteomic analysis | Mus musculus | 1 | ALA4742397 | organism-based format | Patent Bioactivity Data | |
16. | ALA4742608 | B | Inhibition of fatty acid binding protein 4 in mouse 3T3-L1 cells assessed as reduction in sterol carrier protein 2 expression level at 10 uM dosed during day 2 to 6 and followed by drug replacement every 48 hrs by LC-MS/MS analysis based proteomic analysis | Mus musculus | 1 | ALA4742397 | organism-based format | Patent Bioactivity Data | |
17. | ALA4742609 | B | Inhibition of fatty acid binding protein 4 in mouse 3T3-L1 cells assessed as reduction in cytochrome B5 Type A expression level at 10 uM dosed during day 2 to 6 and followed by drug replacement every 48 hrs by LC-MS/MS analysis based proteomic analysis | Mus musculus | 1 | ALA4742397 | organism-based format | Patent Bioactivity Data |