| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1100284 | B | Inhibition of Grp94 | 1 | single protein format | Scientific Literature | |||
| 2. | ALA2212643 | B | Binding affinity at Grp94 incubated for 16 hrs by fluorescence polarization competition assay | 1 | single protein format | Scientific Literature | |||
| 3. | ALA2424061 | B | Binding affinity to GRP94 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 4. | ALA3106549 | B | Binding affinity to human N-terminal polyHis-tagged GRP94 (L69 to N337) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence polarization assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 5. | ALA3242258 | B | Displacement of FITC-geldanamycin from recombinant GRP94 (unknown origin) after 2 hrs by fluorescence polarization assay | Homo sapiens | 37 | single protein format | Scientific Literature | ||
| 6. | ALA3372030 | B | Inhibition of recombinant Grp94 (unknown origin) assessed as tracer bound at 25 uM after 24 hrs by fluorescence polarization assay relative to control | Homo sapiens | 64 | single protein format | Scientific Literature | ||
| 7. | ALA3372031 | B | Inhibition of recombinant Grp94 (unknown origin) assessed as tracer bound after 24 hrs by fluorescence polarization assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 8. | ALA3372032 | B | Inhibition of recombinant Grp94 (unknown origin) assessed as tracer bound at 25 uM after 24 hrs by fluorescence polarization assay relative to HSP90alpha (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 9. | ALA3372036 | B | Binding affinity to Gpr94 in human MDA-MB-231 cells assessed as conformational change using 9G10 antibody by immunoblotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3372037 | B | Inhibition of Gpr94 in human MDA-MB-231 cells assessed as decrease in IGF-II secretion at 1 to 10 uM by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA3372042 | B | Binding affinity to Gpr94 in human RPMI18226 cells using 9G10 antibody by immunoblotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA3372043 | B | Inhibition of Gpr94 in human RPMI18226 cells assessed as decrease in IGF-II secretion at 0.25 to 2 fold antiproliferative IC50 concentration by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA3427924 | B | Displacement of Cy3B-GM from recombinant Grp94 (unknown origin) after 24 hrs by fluorescence polarization assay | Homo sapiens | 70 | single protein format | Scientific Literature | ||
| 14. | ALA3427932 | B | Inhibition of Grp94 in HEK293T cells assessed as downregulation of TLR9 protein expression in post ER compartment after 24 hrs by confocal microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3427935 | B | Inhibition of Grp94 in human SKBR3 cells overexpressing HER2 assessed as degradation of HER2 at 1 to 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3428036 | B | Displacement of FITC-GM from recombinant Grp94 (unknown origin) after 24 hrs by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA3428037 | B | Inhibition of Grp94 in human SKBR3 cells overexpressing HER2 assessed as degradation of HER2 up to 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3428038 | B | Inhibition of Grp94 in human SKBR3 cells overexpressing HER2 assessed as PARP cleavage at 100 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3428039 | B | Inhibition of Grp94 in human SKBR3 cells overexpressing HER2 assessed as degradation of HER2 at 100 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3626591 | B | Inhibition of GRP94 (unknown origin) expressed in HEK293 cells assessed as reduction of Toll-like receptor trafficking to cell membrane treated for 24 hrs prior to testing by DAPI staining-based epifluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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