| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1100285 | B | Inhibition of TRAP1 | 1 | single protein format | Scientific Literature | |||
| 2. | ALA2212642 | B | Binding affinity at TRAP1 incubated for 16 hrs by fluorescence polarization competition assay | 1 | single protein format | Scientific Literature | |||
| 3. | ALA2424059 | B | Binding affinity to TRAP1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA2424065 | B | Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid from recombinant human Trap-1 after 24 hrs by fluorescence polarization assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 5. | ALA2424069 | B | Binding affinity to recombinant human Trap-1 by fluorescence polarization assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA3106548 | B | Binding affinity to human recombinant TRAP1 after 3 hrs by fluorescence polarization assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 7. | ALA3242259 | B | Displacement of FITC-geldanamycin from recombinant TRAP1 (unknown origin) after 2 hrs by fluorescence polarization assay | Homo sapiens | 37 | single protein format | Scientific Literature | ||
| 8. | ALA3427925 | B | Displacement of PU-FITC3 from recombinant TRAP-1 (unknown origin) after 24 hrs by fluorescence polarization assay | Homo sapiens | 69 | single protein format | Scientific Literature | ||
| 9. | ALA4019094 | B | Inhibition of TRAP1 in human HeLa cells assessed as induction of mitochondrial membrane potential loss after 4 hrs by JC-1 staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4019095 | B | Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(DE3) after 24 hrs by fluorescence polarization assay | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 11. | ALA4019097 | B | Inhibition of TRAP1 in human HeLa cells assessed as induction of mitochondrial membrane potential loss at 20 uM after 4 hrs by JC-1 staining based flow cytometry (Rvb = 10.7%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4019098 | B | Inhibition of TRAP1 in human HeLa cells assessed as induction of mitochondrial ROS production after 6 hrs by Mito-Sox staining based flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4019099 | B | Inhibition of TRAP1 in human HeLa cells assessed as elevation of CHOP protein expression at 20 uM after 6 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4019100 | B | Inhibition of TRAP1 in human HeLa cells assessed as cytochrome c release at 20 uM after 4 hrs by Western blot method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4019101 | B | Inhibition of TRAP1 in human HeLa cells assessed as elevation of CHOP protein expression after 6 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4019102 | B | Inhibition of recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) ATPase activity expressed in Escherichia coli BL21(DE3) up to 20 uM preincubated for 30 mins followed by ATP addition measured after 3 hrs by inorganic phosphate color lock gold reagent based assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4124123 | B | Inhibition of recombinant human N-terminal His6-tagged TRAP1 (60 to 704 residues) ATPase activity expressed in Escherichia coli BL21-CodonPlus-RIL after overnight incubation by BioMol green dye-based assay | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 18. | ALA4124125 | B | Inhibition of FITC-geldanamycin binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 704 residues) expressed in Escherichia coli BL21-CodonPlus-RIL by fluorescence anisotropy method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4403664 | B | Inhibition of FITC-geldanamycin binding to N-terminal His-tagged recombinant human TRAP1 (60 to 704 residues) expressed in Escherichia coli preincubated for 2 hrs followed by Geldanamycin-FITC addition and measured after 5 hrs by fluorescence polarization competitive binding assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4604865 | B | Inhibition of recombinant wild-type human TRAP1 ATPase activity expressed in Escherichia coli BL21 (DE3) preincubated for 0.5 hrs followed by ATP addition and measured after 3 hrs by PiColorLock Gold reagent based colorimetric assay | Homo sapiens | 5 | assay format | Scientific Literature |
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