# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1114672 | F | Activation of Nrf2 in rat PC12 cells at 10 uM after 24 hrs by antioxidant response element-driven luciferase reporter gene assay relative to yangonin | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
2. | ALA1114673 | F | Activation of Nrf2 in rat PC12 cells at 10 uM after 24 hrs by antioxidant response element-driven luciferase reporter gene assay relative to kawain | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
3. | ALA1114674 | F | Activation of Nrf2 in rat PC12 cells at 10 uM after 24 hrs by antioxidant response element-driven luciferase reporter gene assay relative to methysticin | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
4. | ALA1114678 | F | Activation of Nrf2 in rat PC12 cells at 10 uM after 24 hrs by antioxidant response element-driven luciferase reporter gene assay | Rattus norvegicus | 3 | ALA1158532 | cell-based format | Scientific Literature | |
5. | ALA1114682 | F | Activation of Nrf2 in rat PC12 cells after 24 hrs by antioxidant response element-driven luciferase reporter gene assay relative to yangonin | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
6. | ALA1114689 | F | Activation of Nrf2 in rat PC12 cells assessed as induction of translocation into nucleus at 10 uM after 30 mins by Western blot analysis | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
7. | ALA1114690 | F | Activation of Nrf2 in rat PC12 cells assessed as induction of translocation into nucleus at 10 uM after 24 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
8. | ALA1176267 | F | Induction of Nrf-mediated NQO1 protein expression in wild type rat NBT2 cells at 25 uM after 24 hrs Western blot analysis | Rattus norvegicus | 2 | ALA1177701 | cell-based format | Scientific Literature | |
9. | ALA1176272 | F | Induction of Nrf in wild type rat NBT2 cells at 25 uM after 24 hrs Western blot analysis | Rattus norvegicus | 2 | ALA1177701 | cell-based format | Scientific Literature | |
10. | ALA1176440 | F | Induction of Nrf-mediated GCL protein expression in wild type rat NBT2 cells at 25 uM after 24 hrs Western blot analysis | Rattus norvegicus | 2 | ALA1177701 | cell-based format | Scientific Literature | |
11. | ALA1176550 | F | Induction of Nrf-mediated GST-alpha protein expression in wild type rat NBT2 cells at 25 uM after 24 hrs Western blot analysis | Rattus norvegicus | 2 | ALA1177701 | cell-based format | Scientific Literature | |
12. | ALA1176551 | F | Induction of Nrf-mediated GST-mu protein expression in wild type rat NBT2 cells at 25 uM after 24 hrs Western blot analysis | Rattus norvegicus | 2 | ALA1177701 | cell-based format | Scientific Literature | |
13. | ALA1694357 | F | Activation of Nrf2/ARE in rat PC12 cells assessed as upregulation of HO-1 protein expression at 10 uM after 12 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA1687931 | cell-based format | Scientific Literature | |
14. | ALA1694358 | F | Induction of nuclear translocation of Nrf2 in rat PC12 cells at 10 uM after 6 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA1687931 | cell-based format | Scientific Literature | |
15. | ALA1694359 | F | Activation of Nrf2/ARE in rat PC12 cells assessed as upregulation of HO-1 protein expression at 10 uM after 6 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA1687931 | cell-based format | Scientific Literature | |
16. | ALA1694360 | F | Activation of Nrf2/ARE in rat PC12 cells assessed as upregulation of HO-1 mRNA expression at 10 uM after 6 hrs by RT-PCR | Rattus norvegicus | 1 | ALA1687931 | cell-based format | Scientific Literature | |
17. | ALA1694361 | F | Activation of Nrf2/ARE in rat PC12 cells assessed as induction of GCSc protein expression at 10 uM by Western blot analysis | Rattus norvegicus | 1 | ALA1687931 | cell-based format | Scientific Literature | |
18. | ALA1694362 | F | Activation of Nrf2/ARE in rat PC12 cells assessed as induction of NQO-1 protein expression by Western blot analysis | Rattus norvegicus | 1 | ALA1687931 | cell-based format | Scientific Literature | |
19. | ALA1694363 | F | Induction of NRF2/ARE enhancer activity rat PC12 cells transfected with ARE-firefly luciferase reporter gene at 10 uM after 24 hrs by luciferase assay | Rattus norvegicus | 8 | ALA1687931 | cell-based format | Scientific Literature | |
20. | ALA1694368 | F | Activation of Nrf2/ARE in rat PC12 cells assessed as HO-1 protein induction at 10 uM after 5 hrs pretreated with p38 inhibitor SB203580 for 1 hr before compound addition by Western blot analysis | Rattus norvegicus | 5 | ALA1687931 | cell-based format | Scientific Literature |