| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1102721 | B | Inhibition of VCP assessed as conversion of ATP to ADP by enzyme coupled glucokinase assay | 27 | single protein format | Scientific Literature | |||
| 2. | ALA1102722 | B | Inhibition of VCP assessed as conversion of ATP to ADP at 10 uM by enzyme coupled glucokinase assay | 19 | single protein format | Scientific Literature | |||
| 3. | ALA1102726 | B | Inhibition of VCP in human HeLa cells assessed as stabilization of ubiquitin-tagged luciferase after 24 hrs by reporter gene assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 4. | ALA1614163 | B | PUBCHEM_BIOASSAY: Luminescence counterscreen assay for p97 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of the C522A mutant p97 ATPase: synthesized compounds. (Class of assay: confirmatory) [Related pubchem assays: 1481, 1517, 1551 ] | Homo sapiens | 16 | single protein format | PubChem BioAssays | ||
| 5. | ALA1614506 | B | PUBCHEM_BIOASSAY: Dose response biochemical high throughput screening assay for inhibitors of the p97 ATPase. (Class of assay: confirmatory) [Related pubchem assays: 1481, 1517 ] | Homo sapiens | 54 | single protein format | PubChem BioAssays | ||
| 6. | ALA1614535 | B | PUBCHEM_BIOASSAY: Luminescence dose response biochemical high throughput screening assay for inhibitors of the p97 ATPase: synthesized compounds. (Class of assay: confirmatory) [Related pubchem assays: 1481, 1517 ] | Homo sapiens | 16 | single protein format | PubChem BioAssays | ||
| 7. | ALA1614140 | B | PUBCHEM_BIOASSAY: Luminescence counterscreen assay for p97 inhibitors: Dose response biochemical high throughput screening assay to identify inhibitors of the C522A mutant p97 ATPase. (Class of assay: confirmatory) [Related pubchem assays: 1481, 1517 ] | Homo sapiens | 54 | single protein format | PubChem BioAssays | ||
| 8. | ALA2321458 | B | Non-competitive inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA2321459 | B | Reversible inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells by serial dilution method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA2321460 | B | Inhibition of VCP in human HCT116 cells assessed as accumulation of C/EBP homologus protein transcription factor at 5 uM after 8 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA2317255 | B | Inhibition of VCP in human HCT116 cells assessed as accumulation of cyclin E at 5 uM after 8 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA2317256 | B | Inhibition of VCP in human HCT116 cells assessed as accumulation of polyubiquitinated proteins at 5 uM after 8 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA2317257 | B | Inhibition of VCP in human HCT116 cells assessed as accumulation of C/EBP homologus protein transcription factor after 8 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA2317258 | B | Inhibition of VCP in human HCT116 cells assessed as accumulation of cyclin E after 8 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA2317271 | B | Inhibition of VCP in human HCT116 cells assessed as accumulation of polyubiquitinated proteins after 8 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA2317274 | B | Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir to substrate addition measured after 90 mins by NADH coupled assay | Homo sapiens | 112 | cell-based format | Scientific Literature | ||
| 17. | ALA3375358 | B | Inhibition of human full length VCP (2 to 806 residues) expressed in High5 insect cells assessed as reduction in ATPase activity by measuring ADP formation by NADH coupled assay | Homo sapiens | 92 | cell-based format | Scientific Literature | ||
| 18. | ALA3375359 | B | Binding affinity to human full length VCP (2 to 806 residues) expressed in High5 insect cells assessed as covalent labeling of Asp478 residues by LC/MS and ESI-MS/MS method based photo affinity labeling assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3379025 | B | Inhibition of VCP in human HCT116 cells assessed as increase in polyubiquitinated protein accumulation at 10 to 20 uM after 8 hrs by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3379026 | B | Inhibition of VCP in human HCT116 cells assessed as induction of CHOP protein expression at 10 to 20 uM after 8 hrs by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature |
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