| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1107397 | F | Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 2. | ALA1107398 | F | Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins by rapid filtration assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA3137173 | F | Antagonist activity at human GPR17 receptor transfected in 1321N1 astrocytoma cells assessed as intracellular calcium mobilization by flurometric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3137174 | F | Agonist activity at human GPR17 receptor transfected in 1321N1 astrocytoma cells assessed as induction of intracellular calcium mobilization by fluorimetric assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 5. | ALA3269448 | B | Binding affinity to human GPR17 expressed in CHO-K1 cell membranes assessed per mg protein after 60 mins by saturation curve study | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3269449 | B | Binding affinity to human GPR17 expressed in CHO-K1 cell membranes after 60 mins by saturation curve study | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3269450 | B | Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes up to 1 uM after 60 mins by liquid scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3269451 | B | Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes assessed as association half life at 100 uM by liquid scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3269452 | B | Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes assessed as dissociation half life at 100 uM treated after 1 hr incubation with radioligand by liquid scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3269453 | B | Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by competition binding assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3269454 | B | Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by homologous competition binding assay in presence of pranlukast | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3269455 | B | Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes up to 1 mM after 60 mins by liquid scintillation counting | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA3269456 | B | Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes at 100 uM after 60 mins by liquid scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3269457 | B | Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA3269458 | B | Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by liquid scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3879920 | F | Agonist activity at recombinant human GPR17 short isoform transfected in human 1321N1 cells assessed as mobilization of intracellular Ca2+ after 20 mins by oregon green 488 BAPTA-1/AM dye-based fluorescence assay | Homo sapiens | 11 | cell-based format | Patent Bioactivity Data | ||
| 17. | ALA3879921 | F | Agonist activity at recombinant human GPR17 short isoform transfected in CHO cells assessed as mobilization of intracellular Ca2+ after 20 mins by oregon green 488 BAPTA-1/AM dye-based fluorescence assay | Homo sapiens | 11 | cell-based format | Patent Bioactivity Data | ||
| 18. | ALA3879922 | F | Agonist activity at recombinant human GPR17 short isoform transfected in human 1321N1 cells assessed as mobilization of intracellular Ca2+ at 0.3 uM after 20 mins by oregon green 488 BAPTA-1/AM dye-based fluorescence assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 19. | ALA3879923 | F | Agonist activity at recombinant human GPR17 short isoform transfected in human 1321N1 cells assessed as mobilization of intracellular Ca2+ at 1 uM after 20 mins by oregon green 488 BAPTA-1/AM dye-based fluorescence assay relative to control | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
| 20. | ALA3879924 | F | Agonist activity at recombinant human GPR17 short isoform transfected in human 1321N1 cells assessed as mobilization of intracellular Ca2+ at 3 uM after 20 mins by oregon green 488 BAPTA-1/AM dye-based fluorescence assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data |
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