# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1107818 | B | Binding affinity to NMUR1 | 4 | ALA1154878 | single protein format | Scientific Literature | ||
2. | ALA3380783 | B | Agonist activity at human NMU1 receptor at 100 uM to 5 mM | Homo sapiens | 30 | ALA3351764 | single protein format | Scientific Literature | |
3. | ALA3362244 | F | Agonist activity at human NMUR1 expressed in HEK293 cells at 1 to 100 nM by calcium mobilization assay relative to NMU | Homo sapiens | 25 | ALA3351814 | cell-based format | Scientific Literature | |
4. | ALA3362613 | F | Agonist activity at human NMUR1 expressed in HEK293 cells at 1 nM by calcium mobilization assay relative to NMU | Homo sapiens | 1 | ALA3351814 | cell-based format | Scientific Literature | |
5. | ALA3362614 | F | Agonist activity at human NMUR1 expressed in HEK293 cells at 10 nM by calcium mobilization assay relative to NMU | Homo sapiens | 1 | ALA3351814 | cell-based format | Scientific Literature | |
6. | ALA3362615 | F | Agonist activity at human NMUR1 expressed in CHO cells assessed as concentration required to induce 50% response by calcium mobilization assay relative to NMU | Homo sapiens | 4 | ALA3351814 | cell-based format | Scientific Literature | |
7. | ALA3362619 | F | Partial agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assay | Homo sapiens | 2 | ALA3351814 | cell-based format | Scientific Literature | |
8. | ALA3362621 | F | Agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assay | Homo sapiens | 1 | ALA3351814 | cell-based format | Scientific Literature | |
9. | ALA3362623 | F | Agonist activity at human NMUR1 expressed in CHO cells at 10'-12 to 10'-6 M by calcium mobilization assay relative to NMU | Homo sapiens | 2 | ALA3351814 | cell-based format | Scientific Literature | |
10. | ALA3428650 | F | Agonist activity at human NMUR1 expressed in CHO cells assessed as intracellular calcium flux at 1 and 10 nM by Fluo-4 AM dye based fluorometric imaging method relative to 1000 nM human neuromedin U | Homo sapiens | 12 | ALA3425508 | cell-based format | Scientific Literature | |
11. | ALA3428652 | F | Agonist activity at human NMUR1 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging method | Homo sapiens | 2 | ALA3425508 | cell-based format | Scientific Literature | |
12. | ALA3428653 | F | Intrinsic agonist activity at human NMUR1 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging method | Homo sapiens | 1 | ALA3425508 | cell-based format | Scientific Literature | |
13. | ALA3760529 | F | Agonist activity at recombinant human NMU1 expressed in HEK293 cells assessed as change in intracellular calcium flux by fluorescence assay | Homo sapiens | 17 | ALA3758116 | cell-based format | Scientific Literature | |
14. | ALA3760530 | F | Agonist activity at recombinant human NMU1 expressed in HEK293 cells assessed as change in intracellular calcium flux by fluorescence assay relative to human NmU | Homo sapiens | 11 | ALA3758116 | cell-based format | Scientific Literature | |
15. | ALA3760531 | F | Agonist activity at recombinant human NMU1 expressed in HEK293 cells assessed as change in intracellular calcium flux at 10 uM by fluorescence assay relative to human NmU | Homo sapiens | 12 | ALA3758116 | cell-based format | Scientific Literature | |
16. | ALA4013732 | A | Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assay | Homo sapiens | 27 | ALA4011647 | cell-based format | Scientific Literature | |
17. | ALA4016655 | F | Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux at 0.1 to 10 nM after 18 hrs by Fluo-4 AM dye based FLIPR assay relative to NMU | Homo sapiens | 6 | ALA4014341 | cell-based format | Scientific Literature | |
18. | ALA4016659 | F | Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux at 0.1 nM after 18 hrs by Fluo-4 AM dye based FLIPR assay relative to NMU | Homo sapiens | 4 | ALA4014341 | cell-based format | Scientific Literature | |
19. | ALA4016660 | F | Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux at 100 nM after 18 hrs by Fluo-4 AM dye based FLIPR assay relative to NMU | Homo sapiens | 1 | ALA4014341 | cell-based format | Scientific Literature | |
20. | ALA4016662 | F | Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux after 18 hrs by Fluo-4 AM dye based FLIPR assay | Homo sapiens | 2 | ALA4014341 | cell-based format | Scientific Literature |