# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1942547 | B | Activation of human PKM2 assessed as ATP product formation after 1 hr by luminescent pyruvate kinase-luciferase coupled assay | Homo sapiens | 81 | single protein format | Scientific Literature | ||
2. | ALA1942548 | B | Activation of human PKM2 assessed as ATP product formation at 57 nM after 1 hr by luminescent pyruvate kinase-luciferase coupled assay | Homo sapiens | 19 | single protein format | Scientific Literature | ||
3. | ALA1942549 | B | Activation of human PKM2 assessed as ATP product formation at 57 uM after 1 hr by luminescent pyruvate-kinase luciferase coupled assay | Homo sapiens | 24 | single protein format | Scientific Literature | ||
4. | ALA1942551 | B | Activation of human PKM2 assessed as ATP product formation at 57 mM after 1 hr by luminescent pyruvate kinase-luciferase coupled assay | Homo sapiens | 31 | single protein format | Scientific Literature | ||
5. | ALA1942552 | B | Activation of PKM1 assessed as ATP product formation at 57.5 uM after 1 hr by luminescent pyruvate kinase-luciferase coupled assay | 4 | single protein format | Scientific Literature | |||
6. | ALA1942639 | B | Activation of human PKM2 assessed as reduction in Km for PEP at 10 uM by after 6 mins by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA1942640 | B | Activation of human PKM2 assessed as effect on Km of ADP at 10 uM by after 6 mins by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA1964061 | F | PUBCHEM_BIOASSAY: qHTS for Activators of Human Muscle Isoform 2 Pyruvate Kinase: Extended Characterization. (Class of assay: confirmatory) | 6 | assay format | PubChem BioAssays | |||
9. | ALA1963856 | F | PUBCHEM_BIOASSAY: qHTS for Activators of Human Muscle Isoform 2 Pyruvate Kinase: Muscle Isoform 1 Assay. (Class of assay: confirmatory) | ⋯ | assay format | PubChem BioAssays | |||
10. | ALA1964008 | F | PUBCHEM_BIOASSAY: qHTS for Activators of Human Muscle Isoform Pyruvate Kinase: Extended Characterization Using A Lactate Dehydrogenase (LDH) Assay. (Class of assay: confirmatory) | 6 | assay format | PubChem BioAssays | |||
11. | ALA1115317 | B | Activation of PKM2 assessed as ATP product formation by luminescent pyruvate kinase-luciferase coupled assay | 57 | single protein format | Scientific Literature | |||
12. | ALA1115318 | B | Activation of PKM2 assessed as ATP product formation at 57 uM by luminescent pyruvate kinase-luciferase coupled assay relative to fructose-1,6-bis-phosphate | 57 | single protein format | Scientific Literature | |||
13. | ALA1115321 | B | Activation of PKM2 assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay | 1 | single protein format | Scientific Literature | |||
14. | ALA1115322 | B | Activation of PKM2 assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay relative to fructose-1,6-bis-phosphate | 1 | single protein format | Scientific Literature | |||
15. | ALA1115323 | B | Activation of PKM1 assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay | 57 | single protein format | Scientific Literature | |||
16. | ALA1115324 | B | Activation of PKM1 assessed as ATP product formation by luminescent pyruvate kinase-luciferase coupled assay | 57 | single protein format | Scientific Literature | |||
17. | ALA1111818 | B | Activation of PKM2 assessed as reduction of Km for phosphoenolpyruvate relative to untreated control | 2 | single protein format | Scientific Literature | |||
18. | ALA1111819 | B | Activation of PKM2 in presence of excess of phosphoenolpyruvate level | 2 | single protein format | Scientific Literature | |||
19. | ALA1111820 | B | Activation of PKM2 assessed as effect on Km for ADP relative to untreated control | 1 | single protein format | Scientific Literature | |||
20. | ALA1120299 | B | Activation of human PKM2 assessed as ATP product formation after 1 hr by luminescent pyruvate kinase-luciferase coupled assay | Homo sapiens | 46 | single protein format | Scientific Literature |