# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1104445 | B | Inhibition of FPPS in rat liver S10 supernatant assessed as conversion of (R,S)-[2-14C]mevalonic acid to [14C]squalene at 1 uM after 60 mins | Rattus norvegicus | 4 | assay format | Scientific Literature | ||
2. | ALA1104446 | B | Inhibition of FPPS in rat liver S10 supernatant assessed as conversion of (R,S)-[2-14C]mevalonic acid to [14C]squalene at 10 uM after 60 mins | Rattus norvegicus | 4 | assay format | Scientific Literature | ||
3. | ALA4367181 | B | Inhibition of farnesyl diphosphate synthase in Sprague-Dawley rat liver S100 fraction using MVA as substrate preincubated for 10 min followed by MVA addition by HPLC analysis | Rattus norvegicus | 1 | subcellular format | Scientific Literature | ||
4. | ALA4722767 | B | Inhibition of rat FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substrate at 10 uM incubated for 10 mins by microplate reader | Rattus norvegicus | 10 | assay format | Scientific Literature | ||
5. | ALA4722768 | B | Binding affinity to rat FPPS expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry | Rattus norvegicus | 10 | assay format | Scientific Literature |