# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3540565 | Binding | Induction of Nrf2 nuclear translocation in BaP-treated neonatal HDF at 10 uM after 2 hrs by DAPI staining-based confocal scanning laser microcopic analysis | Homo sapiens | 1 | ALA3526152 | single protein format | Scientific Literature | |
2. | ALA3540566 | Binding | Induction of Nrf2 nuclear translocation in neonatal HDF at 10 uM after 2 hrs by DAPI staining-based confocal scanning laser microcopic analysis | Homo sapiens | 1 | ALA3526152 | single protein format | Scientific Literature | |
3. | ALA3540567 | Binding | Induction of Nrf2 nuclear translocation in BaP-treated neonatal HDF at 10 uM after 2 hrs by DAPI staining-based confocal scanning laser microcopic analysis in presence of PI3K/Akt inhibitor LY294002 | Homo sapiens | 1 | ALA3526152 | single protein format | Scientific Literature | |
4. | ALA3540568 | Binding | Induction of Nrf2 nuclear translocation in BaP-treated neonatal HDF assessed as upregulation of NQO1 mRNA expression at 10 uM after 24 hrs by real-time PCR analysis relative to BaP-treated control | Homo sapiens | 1 | ALA3526152 | assay format | Scientific Literature | |
5. | ALA3587889 | Binding | Induction of Nrf2 Ser40 phosphorylation in human NPC-TW01 cells expressing pGL4-9ARE incubated for 6 and 12 hrs by Western blot method | Homo sapiens | 4 | ALA3585270 | cell-based format | Scientific Literature | |
6. | ALA3587892 | Binding | Activation of Nrf2 in human NPC-TW01 or HONE1 cells expressing ARE-luciferase at 20 uM incubated for 16 hrs by luciferase reporter gene assay relative to untreated control | Homo sapiens | 23 | ALA3585270 | cell-based format | Scientific Literature | |
7. | ALA3587895 | Binding | Activation of Nrf2 in human NPC-TW01 or HONE1 cells expressing ARE-luciferase at 20 uM incubated for 16 hrs in presence of PKC signaling inhibitor staurosporine by luciferase reporter gene assay relative to untreated control | Homo sapiens | 4 | ALA3585270 | cell-based format | Scientific Literature | |
8. | ALA3588496 | Binding | Activation of Nrf2 in human HepG2-ARE-C8 cells assessed as upregulation of ARE level at 20 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 43 | ALA3585308 | cell-based format | Scientific Literature | |
9. | ALA3588497 | Binding | Activation of Nrf2 in human HepG2-ARE-C8 cells assessed as upregulation of ARE level at 50 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 1 | ALA3585308 | cell-based format | Scientific Literature | |
10. | ALA3588498 | Binding | Activation of Nrf2 in human HepG2-ARE-C8 cells assessed as upregulation of ARE level at 0.2 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 43 | ALA3585308 | cell-based format | Scientific Literature | |
11. | ALA3588499 | Binding | Activation of Nrf2 in human HepG2-ARE-C8 cells assessed as upregulation of ARE level at 0.02 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 43 | ALA3585308 | cell-based format | Scientific Literature | |
12. | ALA3588500 | Binding | Activation of Nrf2 in human HepG2-ARE-C8 cells assessed as upregulation of ARE level at 2 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 43 | ALA3585308 | cell-based format | Scientific Literature | |
13. | ALA3587109 | Binding | Activation of Nrf2 in human HepG2-ARE-C8 cells assessed as upregulation of ARE level at 40 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 43 | ALA3585308 | cell-based format | Scientific Literature | |
14. | ALA3587110 | Binding | Activation of Nrf2 in human HepG2-ARE-C8 cells assessed as upregulation of ARE level at 80 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 43 | ALA3585308 | cell-based format | Scientific Literature | |
15. | ALA3587111 | Binding | Activation of Nrf2 in human HepG2-ARE-C8 cells assessed as upregulation of ARE level at 160 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 43 | ALA3585308 | cell-based format | Scientific Literature | |
16. | ALA3587113 | Binding | Activation of Nrf2 in human HCT116 cells assessed as upregulation of HO-1 expression at 10 uM measured at 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA3585308 | cell-based format | Scientific Literature | |
17. | ALA3587114 | Binding | Activation of Nrf2 in human HCT116 cells assessed as upregulation of NQO1 expression after 6 hrs by Western blot analysis | Homo sapiens | 1 | ALA3585308 | cell-based format | Scientific Literature | |
18. | ALA3587115 | Binding | Activation of Nrf2 in human HCT116 cells after 6 hrs by Western blot analysis | Homo sapiens | 1 | ALA3585308 | cell-based format | Scientific Literature | |
19. | ALA3587116 | Binding | Activation of Nrf2 in human HCT116 cells at 10 uM after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA3585308 | cell-based format | Scientific Literature | |
20. | ALA3587117 | Binding | Activation of Nrf2 in human HCT116 cells at 10 uM by qRT-PCR analysis | Homo sapiens | 1 | ALA3585308 | cell-based format | Scientific Literature |