| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1816043 | B | Binding affinity to human arginase 1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA1816208 | B | Binding affinity to human arginase 1 using L-arginine as substrate by surface plasmon resonance assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 3. | ALA1838747 | B | Displacement of [14C-guanidino]-L-arginine from human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 4. | ALA1108176 | B | Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 5. | ALA1108177 | B | Noncompetitive inhibition of human recombinant arginase 1 by Lineweaver-Burke plot analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA1104707 | B | Competitive inhibition of human recombinant arginase 1 by Lineweaver-Burke plot analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA1104708 | B | Ratio of 2-aminoimidazole Ki to compound Ki for human recombinant arginase 1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA1104709 | B | Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by surface plasmon resonance assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA2330538 | B | Selectivity ratio of IC50 for human arginase 1 transfected in CHO cells to IC50 for human arginase 1 | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA2330539 | B | Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation at 300 uM after 60 mins by spectrophotometric analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA2330667 | B | Inhibition of human arginase 1 transfected in CHO cells assessed as inhibition of urea formation after 24 hrs by spectrophotometric analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA2330669 | B | Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 mins by spectrophotometric analysis | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 13. | ALA2351678 | B | Inhibition of human Arg1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA2351681 | B | Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Homo sapiens | 16 | single protein format | Scientific Literature | ||
| 15. | ALA2423684 | B | Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 16. | ALA5255216 | B | Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysis | Homo sapiens | 15 | single protein format | Scientific Literature | ||
| 17. | ALA5255217 | B | Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assay | Homo sapiens | 16 | single protein format | Scientific Literature | ||
| 18. | ALA5255218 | B | Inhibition of human Arginase I in human myeloid-derived suppressor cells using L-arginine as substrate assessed as L-ornithine product formation by measuring dissociation constant preincubated for 10 mins followed by ninhydrin solution and measured after 1 hrs by colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5255219 | B | Inhibition of human Arginase I assessed as dissociation constant by ITC analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4139714 | B | Inhibition of human arginase 1 assessed as increase in melting temperature up to 25 uM by SYPRO orange dye based differential scanning fluorimetry | Homo sapiens | 1 | single protein format | Scientific Literature |
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