# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1108176 | B | Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assay | Homo sapiens | 6 | ALA1157817 | assay format | Scientific Literature | |
2. | ALA1108177 | B | Noncompetitive inhibition of human recombinant arginase 1 by Lineweaver-Burke plot analysis | Homo sapiens | 1 | ALA1157817 | single protein format | Scientific Literature | |
3. | ALA1104707 | B | Competitive inhibition of human recombinant arginase 1 by Lineweaver-Burke plot analysis | Homo sapiens | 2 | ALA1157817 | single protein format | Scientific Literature | |
4. | ALA1104708 | B | Ratio of 2-aminoimidazole Ki to compound Ki for human recombinant arginase 1 | Homo sapiens | 1 | ALA1157817 | single protein format | Scientific Literature | |
5. | ALA1104709 | B | Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by surface plasmon resonance assay | Homo sapiens | 1 | ALA1157817 | assay format | Scientific Literature | |
6. | ALA1816043 | B | Binding affinity to human arginase 1 | Homo sapiens | 1 | ALA1811917 | single protein format | Scientific Literature | |
7. | ALA1816208 | B | Binding affinity to human arginase 1 using L-arginine as substrate by surface plasmon resonance assay | Homo sapiens | 3 | ALA1811917 | single protein format | Scientific Literature | |
8. | ALA1838747 | B | Displacement of [14C-guanidino]-L-arginine from human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assay | Homo sapiens | 2 | ALA1833881 | assay format | Scientific Literature | |
9. | ALA2330538 | B | Selectivity ratio of IC50 for human arginase 1 transfected in CHO cells to IC50 for human arginase 1 | Homo sapiens | 2 | ALA2321686 | cell-based format | Scientific Literature | |
10. | ALA2330539 | B | Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation at 300 uM after 60 mins by spectrophotometric analysis | Homo sapiens | 1 | ALA2321686 | assay format | Scientific Literature | |
11. | ALA2330667 | B | Inhibition of human arginase 1 transfected in CHO cells assessed as inhibition of urea formation after 24 hrs by spectrophotometric analysis | Homo sapiens | 4 | ALA2321686 | cell-based format | Scientific Literature | |
12. | ALA2330669 | B | Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 mins by spectrophotometric analysis | Homo sapiens | 16 | ALA2321686 | assay format | Scientific Literature | |
13. | ALA2351678 | B | Inhibition of human Arg1 | Homo sapiens | 1 | ALA2346653 | single protein format | Scientific Literature | |
14. | ALA2351681 | B | Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Homo sapiens | 16 | ALA2346653 | single protein format | Scientific Literature | |
15. | ALA2423684 | B | Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Homo sapiens | 18 | ALA2417426 | single protein format | Scientific Literature | |
16. | ALA4139714 | B | Inhibition of human arginase 1 assessed as increase in melting temperature up to 25 uM by SYPRO orange dye based differential scanning fluorimetry | Homo sapiens | 1 | ALA4138110 | single protein format | Scientific Literature | |
17. | ALA4158868 | B | Inhibition of full length human arginase 1 expressed in Escherichia coli BL21(DE3) at 200 uM using unlabeled L-arginine/L-[guanidino-14C]arginine as substrate after 5 mins by liquid scintillation counting method relative to control | Homo sapiens | 25 | ALA4152388 | assay format | Scientific Literature | |
18. | ALA4184939 | B | Binding affinity to arginase 1 (unknown origin) | Homo sapiens | 1 | ALA4184111 | single protein format | Scientific Literature | |
19. | ALA4232766 | B | Irreversible inhibition of human arginase 1 using thioarginine as substrate measured up to 360 mins by UV micro plate method | Homo sapiens | 2 | ALA4229409 | single protein format | Scientific Literature | |
20. | ALA4232767 | B | Irreversible inhibition of human arginase 1 assessed as inactivation rate constant using thioarginine as substrate measured up to 360 mins by UV micro plate method | Homo sapiens | 2 | ALA4229409 | single protein format | Scientific Literature |