| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1073732 | B | Inhibition of LRRK2 at 3 to 6 uM relative to control | 1 | single protein format | Scientific Literature | |||
| 2. | ALA1102582 | B | Inhibition of LRRK2 at 10 uM | 2 | single protein format | Scientific Literature | |||
| 3. | ALA1102583 | B | Inhibition of LRRK2 G2019S mutant at 10 uM | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 4. | ALA1174882 | B | Inhibition of LRRK2 at 10 uM | 2 | single protein format | Scientific Literature | |||
| 5. | ALA1174883 | B | Inhibition of LRRK2 G2019S mutant at 10 uM | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 6. | ALA1633362 | B | Inhibition of LRKK2 at 10 uM | 1 | single protein format | Scientific Literature | |||
| 7. | ALA1633363 | B | Inhibition of LRKK2 G2019S mutant at 10 uM | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 8. | ALA1648805 | B | Inhibition of LRRK2 at 10 uM after 60 mins by TR-FRET assay | 6 | single protein format | Scientific Literature | |||
| 9. | ALA1686786 | B | Inhibition of LRRK2 at 10 uM | 1 | single protein format | Scientific Literature | |||
| 10. | ALA1772597 | B | Inhibition of purified N-terminal GST-tagged LRRK2 G2019S mutant autophosphorylation activity using [gamma32-P]ATP | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA1772599 | B | Inhibition of purified N-terminal GST-tagged LRRK2 G2019S mutant autophosphorylation activity using myelin basic protein as substrate | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA1772600 | B | Inhibition of purified N-terminal GST-tagged LRRK2 G2019S mutant assessed as residual activity of enzyme at 10 uM | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA1772601 | B | Inhibition of purified N-terminal GST-tagged LRRK2 G2019S mutant assessed as residual activity of enzyme at 25 uM | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA1772650 | B | Inhibition of LRRK2 G2019S mutant expressed in mouse SN4741 cells assessed as reduction in hydrogen peroxide-induced neurotoxicity at 10 uM by measuring cell survival after 48 hrs by crystal violet assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA1772651 | B | Inhibition of wild type LRRK2 expressed in mouse SN4741 cells assessed as reduction in hydrogen peroxide-induced neurotoxicity at 10 uM by measuring cell survival after 48 hrs by crystal violet assay relative to control | 2 | cell-based format | Scientific Literature | |||
| 16. | ALA1772654 | B | Inhibition of purified N-terminal GST-tagged LRRK2 G2019S mutant autophosphorylation activity using myelin basic protein as substrate at 25 uM | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 17. | ALA1787817 | B | Inhibition of LRRK2 at 10 uM | 1 | single protein format | Scientific Literature | |||
| 18. | ALA1825776 | B | Inhibition of LRRK2 at 10 uM | 1 | single protein format | Scientific Literature | |||
| 19. | ALA1908437 | B | Binding constant for LRRK2 kinase domain | 72 | single protein format | Scientific Literature | |||
| 20. | ALA1908438 | B | Binding constant for LRRK2(G2019S) kinase domain | 72 | single protein format | Scientific Literature |
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