| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1119385 | B | Binding affinity to Influenza A virus (A/Puerto Rico/8/34(H1N1)) hemagglutininin by phage ELISA | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 5 | ALA1155549 | single protein format | Scientific Literature | |
| 2. | ALA1935837 | B | Inhibition of Human influenza virus A/PR/8/34 (H1N1) hemagglutininin activity in chicken erythrocytes after 1 hr | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 3 | ALA1932915 | cell-based format | Scientific Literature | |
| 3. | ALA4136989 | B | Inhibition of Influenza A virus A/PR/8/34 HA1 domain assessed as reduction in virus-induced aggregation of chicken erythrocytes at 0.75 to 1500 uM incubated for 1 hr with virus followed by transfer of compound-virus preparation to chicken erythrocytes solution measured after 40 mins | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4130623 | assay format | Scientific Literature | |
| 4. | ALA4136999 | B | Inhibition of Influenza A virus A/PR/8/34 HA2-mediated hemolysis preincubated with virus for 30 mins followed by chicken red blood cells addition measured after 30 mins by spectrophotometric analysis | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4130623 | assay format | Scientific Literature | |
| 5. | ALA4201459 | B | Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Hemagglutinin 1-induced aggregation of chicken erythrocytes at 0.05 to 100 uM | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4196194 | assay format | Scientific Literature | |
| 6. | ALA4201460 | B | Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Hemagglutinin 2-mediated hemolysis of chicken erythrocytes at acidic pH conditions | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4196194 | assay format | Scientific Literature | |
| 7. | ALA4385003 | B | Inhibition of Influenza A virus (A/PR/8/34(H1N1)) HA-mediated chicken erythrocytes hemagglutination preincubated for 30 mins followed by erythrocytes addition and measured for 1 hr | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4382263 | assay format | Scientific Literature | |
| 8. | ALA4412185 | B | Binding affinity to recombinant Influenza A virus (A/California/04/2009 (H1N1)) hemagglutinin by SPR assay | Influenza A virus (A/California/04/2009(H1N1)) | 3 | ALA4411280 | single protein format | Scientific Literature | |
| 9. | ALA4621364 | B | Inhibition of Hemagglutinin in Influenza A virus (A/Puerto Rico/8/1934(H1N1)) assessed as reduction in virus-induced aggregation of chicken erythrocytes at 3.125 to 50 ug/mL incubated for 60 mins by hemagglutination assay | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4619773 | assay format | Scientific Literature | |
| 10. | ALA4621365 | B | Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Hemagglutinin expressed in African green monkey Vero cells assessed as reduction in virus-induced syncytium formation at 50 ug/ml pre-treated with trypsin followed by compound addition for 15 mins and measured after 2 hrs at pH 5 by HA syncytium assay | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4619773 | cell-based format | Scientific Literature | |
| 11. | ALA4621368 | B | Binding affinity to Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Hemagglutinin at 1.5625 to 50 uM by SPR assay | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 4 | ALA4619773 | single protein format | Scientific Literature | |
| 12. | ALA4621369 | B | Binding affinity to Influenza A virus (A/California/04/2009(H1N1)) Hemagglutinin at 1.5625 to 50 uM by SPR assay | Influenza A virus (A/California/04/2009(H1N1)) | 3 | ALA4619773 | single protein format | Scientific Literature | |
| 13. | ALA4621374 | B | Inhibition of conformational changes in Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Hemagglutinin assessed as increase in retention amount of HA1 subunit on HA proteins at 25 to 50 ug/ml added before acidification incubated for 1 hr by conformational change inhibition assay | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4619773 | single protein format | Scientific Literature | |
| 14. | ALA4621375 | B | Inhibition of trypsin-mediated cleavage of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Hemagglutinin (HA0) at 50 ug/ml incubated for 30 mins by Coomassie blue fast staining and SDS-PAGE gel based trypsin susceptibility assay | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4619773 | single protein format | Scientific Literature | |
| 15. | ALA4621376 | B | Inhibition of Hemagglutinin in Influenza A virus (A/Puerto Rico/8/1934(H1N1))/H1N1 pseudovirus infected in 293FT cells assessed as reduction in virus infection at 50 ug/ml pre-treated with virus before infection and measured after 48 hrs by inverted fluorescence microscopy | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4619773 | cell-based format | Scientific Literature | |
| 16. | ALA4623580 | B | Inhibition of Hemagglutinin in Influenza A virus (A/Puerto Rico/8/34(H1N1)) assessed as reduction in virus-induced agglutination of chicken erythrocytes at 50 uM | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4622861 | assay format | Scientific Literature | |
| 17. | ALA4623581 | B | Inhibition of Hemagglutinin in Influenza A virus (A/Puerto Rico/8/34(H1N1)) assessed as reduction in virus-induced agglutination of chicken erythrocytes at 100 uM | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4622861 | assay format | Scientific Literature | |
| 18. | ALA4686573 | B | Inhibition of Influenza A virus (A/PR 8/34 (H1N1)) hemagglutinin transfected in human HeLa cells assessed as reduction in low pH-indued polykaryon formation at 100 uM preincubated for 15 mins followed by pH 5.2 buffer addition and measured after 5 mins by giemsa staining based microscopic analysis | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4680243 | cell-based format | Scientific Literature | |
| 19. | ALA4686574 | B | Inhibition of Influenza A virus (A/PR 8/34 (H1N1)) hemagglutinin transfected in human HeLa cells assessed as reduction in low pH-indued polykaryon formation preincubated for 15 mins followed by pH 5.2 buffer addition and measured after 5 mins by giemsa staining based microscopic analysis | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4680243 | cell-based format | Scientific Literature | |
| 20. | ALA4686578 | B | Inhibition of Influenza A virus (A/PR 8/34 (H1N1)) hemagglutinin infected in MDCK cells assessed as reduction in virus binding to cell surface | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4680243 | cell-based format | Scientific Literature |
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