| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1118768 | B | Binding affinity to WDR5 expressed in pLysS cells by optimized fluorescent polarization based competitive binding assay | 25 | cell-based format | Scientific Literature | |||
| 2. | ALA1118769 | B | Binding affinity to WDR5 expressed in pLysS cells after 24 hrs by optimized fluorescent polarization based saturation binding assay | 5 | cell-based format | Scientific Literature | |||
| 3. | ALA2339612 | B | Displacement of MLL-WIN N-terminal FITC-tagged GSARAEVHLRKS peptide from human WDR5 (1-334) by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA2339613 | B | Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by fluorescence polarization assay | Homo sapiens | 39 | assay format | Scientific Literature | ||
| 5. | ALA2339614 | B | Antagonist activity at WDR5 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA3801640 | B | Inhibition of human poly His-tagged WDR5 (1 to 334 residues) interaction with MLL1 assessed as displacement of fluorescein isothiocyanate labelled H3 (1 to 15 residues) peptide from WDR5 expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by fluorescence polarization assay | Homo sapiens | 54 | cell-based format | Scientific Literature | ||
| 7. | ALA3801641 | B | Inhibition of human poly His-tagged WDR5 (1 to 334 residues) interaction with MLL1 assessed as displacement of fluorescein isothiocyanate labelled 9-Ala-FAM peptide substrate from WDR5 expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by fluorescence polarization assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 8. | ALA3801642 | B | Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resonance analysis | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 9. | ALA3801643 | B | Inhibition of N-terminal His-tagged WDR5 (24 to 334 residues) (unknown origin) interaction with MLL1 assessed as displacement of 5-Lys-FAM peptide substrate from WDR5 expressed in Escherichia coli Rosetta2(DE3) pLysS cells by fluorescence polarization assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3801645 | B | Inhibition of SUMO-His-tagged WDR5 (unknown origin) interaction with MLL1 assessed as displacement of fluorescence labelled Ac-ARA peptide substrate from WDR5 expressed in Escherichia coli BL21(DE3) pLysS cells by fluorescence polarization assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3803350 | B | Inhibition of WDR5 interaction with MLL1 in human AML cells expressing mutant N-terminal C/EBPalpha assessed as reduction in cell viability at 5 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3824741 | B | Binding affinity to His-tagged human WDR5 expressed in Escherichia coli by isothermal titration calorimetry | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 13. | ALA3824742 | B | Inhibition of 10mer-Thr-FAM probe binding to His-tagged human WDR5 expressed in Escherichia coli incubated for 2 hrs by fluorescence polarization assay | Homo sapiens | 25 | assay format | Scientific Literature | ||
| 14. | ALA3824743 | B | Binding affinity to His-tagged human WDR5 expressed in Escherichia coli BL21 by isothermal titration calorimetry | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA3859082 | B | Binding affinity to WDR5 (unknown origin) at 200 uM by DSF assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3859786 | B | Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay | Homo sapiens | 22 | single protein format | Scientific Literature | ||
| 17. | ALA3859794 | B | Inhibition of C-terminal 5-FAM-WIN peptide binding to N-terminal His-tagged WDR5 (24 to 334 residues) (unknown origin) expressed in Rosetta2-(DE3) pLysS cells after 5 hrs by fluorescence polarization assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3859796 | B | Inhibition of N-terminal FITC-GSARAEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA3875502 | B | Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay | Homo sapiens | 48 | single protein format | Scientific Literature | ||
| 20. | ALA3875503 | B | Binding affinity to human WDR5 by isothermal titration calorimetry | Homo sapiens | 3 | single protein format | Scientific Literature |
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