# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2363193 | Functional | SANGER: Inhibition of human Detroit562 cell growth in a cell viability assay. | Homo sapiens | 98 | ALA1201861 | cell-based format | Sanger Institute Genomics of Drug Sensitivity in Cancer | |
2. | ALA4050896 | Functional | Antiproliferative activity against human Detroit 562 cells after 72 hrs by SRB assay | Homo sapiens | 2 | ALA4049418 | cell-based format | Scientific Literature | |
3. | ALA4201864 | ADME | Effect on cell proliferation of human Detroit 562 cells at 100 to 500 nM incubated for 48 hrs by BrdU incorporation assay | Homo sapiens | 1 | ALA4196210 | cell-based format | Scientific Literature | |
4. | ALA4201866 | ADME | Effect on EMT switch in human Detroit 562 cells at 100 to 500 nM incubated for 48 hrs | Homo sapiens | 1 | ALA4196210 | cell-based format | Scientific Literature | |
5. | ALA4320718 | Functional | Cytotoxicity against human Detroit 562 cells assessed as reduction in cell viability after 4 hrs by MTT assay | Homo sapiens | 2 | ALA4316598 | cell-based format | Scientific Literature | |
6. | ALA4414041 | Functional | Antiproliferative activity against human Detroit 562 cells after 24 hrs by Celltiter-Glo assay | Homo sapiens | 4 | ALA4411331 | cell-based format | Scientific Literature | |
7. | ALA4414044 | Functional | Antitumor activity against human Detroit 562 cells xenografted in NU/NU mouse assessed as reduction in tumor volume at 20 to 80 mg/kg, po administered BID and measured after 21 days | Homo sapiens | 1 | ALA4411331 | organism-based format | Scientific Literature | |
8. | ALA4414045 | Functional | Antitumor activity against human Detroit 562 cells xenografted in NU/NU mouse assessed as tumor stasis at 40 mg/kg, po administered BID and measured after 21 days relative to control | Homo sapiens | 1 | ALA4411331 | organism-based format | Scientific Literature | |
9. | ALA4414046 | Functional | Antitumor activity against human Detroit 562 cells xenografted in NU/NU mouse assessed as tumor regression at 80 mg/kg, po administered BID and measured after 14 days post dose relative to control | Homo sapiens | 1 | ALA4411331 | organism-based format | Scientific Literature | |
10. | ALA4667795 | Functional | Antiproliferative activity against human Detroit 562 cells incubated for 72 hrs by MTT assay | Homo sapiens | 1 | ALA4665661 | cell-based format | Scientific Literature | |
11. | ALA5129771 | Functional | Antiproliferative activity against human Detroit 562 cells assessed as reduction in cell viability incubated for 72 hrs | Homo sapiens | 1 | ALA5126602 | cell-based format | Scientific Literature | |
12. | ALA5161959 | Functional | Cytotoxicity against human Detroit 562 cells assessed as reduction of cell viability up to 10 uM incubated for 72 hrs by celltiter-glo assay | Homo sapiens | 1 | ALA5154806 | cell-based format | Scientific Literature | |
13. | ALA5226956 | Functional | Cytotoxicity against human Detroit 562 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 3 | ALA5226289 | cell-based format | Scientific Literature | |
14. | ALA5261870 | Functional | Cytotoxicity against human Detroit 562 cells measured after 8 days | Homo sapiens | 2 | ALA5260810 | cell-based format | Scientific Literature |