| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1803842 | F | Cytostatic activity against human DMS53 cells assessed as inhibition of cell proliferation after 2 days by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA2215546 | F | Antitumor activity against human DMS53 cell xenografted BALB/c nu/nu mouse assessed as reduction in tumor volume at 20 mg/kg, po administered for 3 times a week measured after 20 days (Rvb = 997 155 mm'3) | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2211677 | F | Antitumor activity against human DMS53 cell xenografted BALB/c nu/nu mouse assessed as reduction in tumor volume at 7.5 mg/kg, po administered for 3 times a week measured after 20 days (Rvb = 997 155 mm'3) | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA2211690 | F | Antitumor activity against human DMS53 cells xenografted in BALB/c nu/nu mouse assessed as reduction in tumor weight at 8 mg/kg, iv administered for 5 days per week measured after 21 days (Rvb = 0.830.11 g) | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA2211691 | F | Antitumor activity against human DMS53 cells xenografted in BALB/c nu/nu mouse assessed as reduction in tumor weight at 4 mg/kg, iv administered for 5 days a week measured after 21 days (Rvb = 0.830.11 g) | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA2211693 | F | Antitumor activity against human DMS53 cells xenografted in BALB/c nu/nu mouse assessed as reduction of tumor volume at 4 mg/kg, iv administered for 5 days a week measured after 21 days (RVb = 922 94 mm'3) | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA2214118 | F | Antitumor activity against human DMS53 cells xenografted in BALB/c nu/nu mouse assessed as reduction of tumor volume at 6 mg/kg, iv administered for 5 days a week measured after 21 days (RVb = 922 94 mm'3) | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA2214119 | F | Antitumor activity against human DMS53 cells xenografted in BALB/c nu/nu mouse assessed as reduction of tumor volume at 3 mg/kg, iv administered for 5 days a week measured after 21 days (RVb = 922 94 mm'3) | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA2214120 | F | Antitumor activity against human DMS53 cells xenografted BALB/c nu/nu mouse assessed as reduction of tumor volume at 0.75 mg/kg, iv administered for 5 days a week measured after 21 days (RVb = 922 94 mm'3) | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA2214123 | F | Antitumor activity against human DMS53 cell xenografted BALB/c nu/nu mouse assessed as reduction in tumor volume at 10 mg/kg, po administered for 3 times a week measured after 20 days (Rvb = 997 155 mm'3) | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
| 11. | ALA2214127 | F | Antiproliferative activity at human DMS53 cells after 72 hrs by MTT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 12. | ALA2214132 | F | Antitumor activity against human DMS53 cells xenografted in BALB/c nu/nu mouse assessed as reduction of tumor volume at 8 mg/kg, iv administered for 5 days a week measured after 21 days (RVb = 922 94 mm'3) | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA2363183 | F | SANGER: Inhibition of human DMS-53 cell growth in a cell viability assay. | Homo sapiens | 46 | cell-based format | Sanger Institute Genomics of Drug Sensitivity in Cancer | ||
| 14. | ALA3803114 | F | Induction of apoptosis in human DMS53 cells harboring p53 mutant assessed as caspase-3 cleavage at 5 to 10 uM after 12 hrs by immunoblotting method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA3803115 | F | Induction of apoptosis in human DMS53 cells harboring p53 mutant assessed as cytochrome c release at 5 to 10 uM after 12 hrs by immunoblotting method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA3803116 | F | Induction of apoptosis in human DMS53 cells harboring p53 mutant assessed as PARP cleavage at 5 to 10 uM after 12 hrs by immunoblotting method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA5054339 | F | Anticancer activity against human DMS-53 cells | Homo sapiens | 1 | cell-based format | Scientific Literature |
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