| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA967703 | F | Cytotoxicity against human NCI-H1581 cells assessed as fraction of viable cells after 72 hrs relative to control | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA979760 | F | Cytotoxicity against human NCI-H1581 cells expressing wild type BRAF at 0.2 uM assessed as fraction of viable cells after 72 hrs relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA979761 | F | Cytotoxicity against human NCI-H1581 cells expressing wild type BRAF at 2 uM assessed as fraction of viable cells after 72 hrs relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA2363477 | F | SANGER: Inhibition of human NCI-H1581 cell growth in a cell viability assay. | Homo sapiens | 137 | cell-based format | Sanger Institute Genomics of Drug Sensitivity in Cancer | ||
| 5. | ALA3830045 | F | Antiproliferative activity against FGFR1-amplified human NCI-H1581 cells after 72 hrs by CCK8/MTT assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 6. | ALA3830195 | F | Antitumor activity against FGFR1-amplified human NCI-H1581 cells xenografted in nude mouse assessed as tumor growth inhibition at 2 mg/kg, po qd administered for 21 days measured on day 21 post last dose relative to vehicle-treated control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA3830196 | F | Antitumor activity against human NCI-H1581 cells xenografted in nude mouse assessed as tumor growth inhibition at 10 mg/kg, po qd administered for 21 days measured on day 21 post last dose relative to vehicle-treated control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA3830197 | F | Antitumor activity against human NCI-H1581 cells xenografted in nude mouse assessed as tumor growth inhibition at 20 mg/kg administered as qd for 21 days measured on day 21 post last dose relative to vehicle-treated control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA3830198 | F | Antitumor activity against human NCI-H1581 cells xenografted in po dosed nude mouse assessed as tumor growth inhibition administered as qd for 21 days measured on day 21 post last dose | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4002776 | F | Antiproliferative activity against FGFR2-amplified human NCI-H1581 cells after 72 hrs by CCK8/SRB assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4002791 | F | Antitumor activity against FGFR1-amplified human NCI-H1581 cells xenografted in nude mouse assessed as tumor growth inhibition at 20 mg/kg, po qd administered for 10 days and measured on day 10 post last dose relative to vehicle-treated control | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA4002793 | F | Antitumor activity against FGFR1-amplified human NCI-H1581 cells xenografted in nude mouse assessed as tumor growth inhibition at 5 mg/kg, po qd administered for 10 days and measured on day 10 post last dose relative to vehicle-treated control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4018682 | F | Antitumor activity against human NCI-H1581 cells xenografted in nude mouse assessed as tumor growth inhibition at 5 mg/kg, po qd administered for 14 days measured twice per week during compound dosing | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4018683 | F | Antitumor activity against human NCI-H1581 cells xenografted in nude mouse assessed as tumor growth inhibition at 20 mg/kg, po qd administered for 14 days measured twice per week during compound dosing | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4018710 | F | Antitumor activity against human NCI-H1581 cells xenografted in po dosed nude mouse assessed as tumor growth inhibition administered as qd for 14 days measured twice per week during compound dosing | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4271706 | F | Antiproliferative activity against human NCI-H1581 cells expressing FGFR1 after 72 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4382841 | F | Antiproliferative activity against FGFR1 amplified human NCI-H1581 cells after 72 hrs by CCK8 or MTT assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
| 18. | ALA4382879 | F | Antitumor activity against FGFR1 amplified human NCI-H1581 cells xenografted in po dosed nude mouse assessed as tumor growth inhibition administered once daily for 14 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4382881 | F | Antitumor activity against FGFR1 amplified human NCI-H1581 cells xenografted in nude mouse assessed as tumor growth inhibition at 100 mg/kg, po administered once daily for 14 days relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4412432 | F | Antitumor activity against human NCI-H1581 cells xenografted in nude mouse assessed as tumor growth inhibition at 10 mg/kg, po qd for 7 to 10 days relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature |
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