# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA976885 | F | Cytotoxicity against human SNU449 cells expressing wild type EGFR at 2 uM assessed as fraction of viable cells after 72 hrs relative to control | Homo sapiens | 2 | ALA1149823 | cell-based format | Scientific Literature | |
2. | ALA970348 | F | Cytotoxicity against human SNU449 cells assessed as fraction of viable cells after 72 hrs relative to control | Homo sapiens | 10 | ALA1149823 | cell-based format | Scientific Literature | |
3. | ALA977035 | F | Cytotoxicity against human SNU449 cells expressing wild type BRAF at 0.2 uM assessed as fraction of viable cells after 72 hrs relative to control | Homo sapiens | 1 | ALA1149823 | cell-based format | Scientific Literature | |
4. | ALA977036 | F | Cytotoxicity against human SNU449 cells expressing wild type BRAF at 2 uM assessed as fraction of viable cells after 72 hrs relative to control | Homo sapiens | 1 | ALA1149823 | cell-based format | Scientific Literature | |
5. | ALA1943532 | F | Cytotoxicity against human SNU449 cells at 50 uM after 48 hrs | Homo sapiens | 2 | ALA1938375 | cell-based format | Scientific Literature | |
6. | ALA1943533 | F | Cytotoxicity against human SNU449 cells at 50 uM after 72 hrs | Homo sapiens | 2 | ALA1938375 | cell-based format | Scientific Literature | |
7. | ALA1943534 | F | Cytotoxicity against human SNU449 cells after 48 hrs | Homo sapiens | 2 | ALA1938375 | cell-based format | Scientific Literature | |
8. | ALA1943535 | F | Cytotoxicity against human SNU449 cells after 72 hrs | Homo sapiens | 2 | ALA1938375 | cell-based format | Scientific Literature | |
9. | ALA1943636 | F | Cell cycle arrest in human SNU449 cells assessed as accumulation at G1 phase at 25 uM after 48 to 72 hrs using annexin V/propidium iodide staining by flow cytometric analysis | Homo sapiens | 1 | ALA1938375 | cell-based format | Scientific Literature | |
10. | ALA1943637 | F | Cell cycle arrest in human SNU449 cells assessed as accumulation at G1 phase at 50 uM after 72 hrs using annexin V/propidium iodide staining by flow cytometric analysis | Homo sapiens | 1 | ALA1938375 | cell-based format | Scientific Literature | |
11. | ALA1942313 | F | Cell cycle arrest in human SNU449 cells assessed as accumulation at G1 phase at 100 uM after 48 to 72 hrs using annexin V/propidium iodide staining by flow cytometric analysis | Homo sapiens | 2 | ALA1938375 | cell-based format | Scientific Literature | |
12. | ALA1942314 | F | Cell cycle arrest in human SNU449 cells assessed as accumulation at S phase at 100 uM after 48 to 72 hrs using annexin V/propidium iodide staining by flow cytometric analysis | Homo sapiens | 2 | ALA1938375 | cell-based format | Scientific Literature | |
13. | ALA1942315 | F | Decrease of cyclin D1 level in human SNU449 cells at 50 uM after 72 hrs by Western blotting relative to beta-actin | Homo sapiens | 2 | ALA1938375 | cell-based format | Scientific Literature | |
14. | ALA1942316 | F | Effect on p27 expression in human SNU449 cells at 50 uM after 72 hrs by Western blotting relative to beta-actin | Homo sapiens | 2 | ALA1938375 | cell-based format | Scientific Literature | |
15. | ALA1942317 | F | Up-regulation of p21 expression in human SNU449 cells at 50 uM after 72 hrs by Western blotting relative to beta-actin | Homo sapiens | 2 | ALA1938375 | cell-based format | Scientific Literature | |
16. | ALA1942318 | F | Up-regulation of p53 expression in human SNU449 cells at 50 uM after 72 hrs by Western blotting relative to beta-actin | Homo sapiens | 2 | ALA1938375 | cell-based format | Scientific Literature | |
17. | ALA1942321 | F | Induction of apoptosis in human SNU449 cells at 50 to 100 uM after 72 hrs using annexin V/propidium iodide staining by flow cytometric analysis | Homo sapiens | 2 | ALA1938375 | cell-based format | Scientific Literature | |
18. | ALA2032766 | F | Antiproliferative activity against human SNU449 after 72 hrs by CellTiter Glo assay | Homo sapiens | 5 | ALA2029236 | cell-based format | Scientific Literature | |
19. | ALA2175188 | F | Cytotoxicity against human SNU449 cells with intact TGFbeta pathway assessed as growth inhibition at 250 uM after 72 hrs by MTT assay | Homo sapiens | 1 | ALA2169778 | cell-based format | Scientific Literature | |
20. | ALA2363668 | F | SANGER: Inhibition of human SNU-449 cell growth in a cell viability assay. | Homo sapiens | 97 | ALA1201861 | cell-based format | Sanger Institute Genomics of Drug Sensitivity in Cancer |