# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1168790 | B | Inhibition of ASK2 at 1 uM | 8 | ALA1165965 | single protein format | Scientific Literature | ||
2. | ALA1174072 | B | Inhibition of ASK2 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
3. | ALA1244728 | B | Binding affinity to ASK2 | 7 | ALA1240346 | single protein format | Scientific Literature | ||
4. | ALA1827645 | B | Activity of ASK2 kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
5. | ALA1908659 | B | Binding constant for ASK2 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
6. | ALA2212073 | B | Inhibition of ASK2 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
7. | ALA2214714 | B | Inhibition of ASK2 | 1 | ALA2203246 | single protein format | Scientific Literature | ||
8. | ALA3631908 | B | Inhibition of MEKK6 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | ALA3627608 | single protein format | Scientific Literature | |
9. | ALA3991763 | B | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 238 | ALA3991601 | subcellular format | Kuster lab chemical proteomics drug profiling | |
10. | ALA4012569 | B | Binding affinity to MAP3K6 in human INA-6 cells after 3 hrs by nanoLC-MS/MS method | Homo sapiens | 2 | ALA4011617 | cell-based format | Scientific Literature | |
11. | ALA4025017 | B | Inhibition of wild-type human partial length ASK2 (M278 to R972 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
12. | ALA4034388 | B | Inhibition of MAP3K6 Lysine 2 labelling site (unknown origin) at 10 uM | Homo sapiens | 1 | ALA4033637 | single protein format | Scientific Literature | |
13. | ALA4043828 | B | Inhibition of wild-type human partial length ASK2 (M278 to R972 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
14. | ALA4045742 | B | Inhibition of MAP3K6 conserved Lys1 (IAIKEIPER) in human PBMC at 1 uM | Homo sapiens | 1 | ALA4043168 | single protein format | Scientific Literature | |
15. | ALA4045748 | B | Inhibition of MAP3K6 conserved Lys2 (DIKGDNVLINTFSGLLK) in human PBMC at 1 uM | Homo sapiens | 1 | ALA4043168 | single protein format | Scientific Literature | |
16. | ALA4045983 | B | Inhibition of MAP3K6 conserved Lys1 (IAIKEIPER) in human PBMC at 0.1 uM | Homo sapiens | 1 | ALA4043168 | single protein format | Scientific Literature | |
17. | ALA4045989 | B | Inhibition of MAP3K6 conserved Lys2 (DIKGDNVLINTFSGLLK) in human PBMC at 0.1 uM | Homo sapiens | 1 | ALA4043168 | single protein format | Scientific Literature | |
18. | ALA4054946 | B | Inhibition of wild-type human partial length MAP3K6 (M278 to R972 residues) expressed in mammalian expression system assessed as residual activity at 50 nM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4052645 | assay format | Scientific Literature | |
19. | ALA4156907 | B | Binding affinity to wild-type human partial length ASK2 (M278 to R972 residues) expressed in mammalian expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4152344 | assay format | Scientific Literature | |
20. | ALA4185686 | B | Binding affinity to wild-type human partial length ASK2 (M278 to R972 residues) expressed in HEK293 cells at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4184148 | cell-based format | Scientific Literature |