# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3631273 | Binding | Inhibition of LCK2 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | ALA3627608 | single protein format | Scientific Literature | |
2. | ALA3748235 | Binding | Inhibition of human LCK2 using MBP as substrate | Homo sapiens | 1 | ALA3745707 | single protein format | Scientific Literature | |
3. | ALA3776233 | Binding | Inhibition of N-terminal His6-tagged recombinant human LCK2 expressed in baculovirus infected insect Sf9 cells assessed as remaining activity at 1 uM relative to control | Homo sapiens | 3 | ALA3774357 | cell-based format | Scientific Literature | |
4. | ALA1166021 | Binding | Inhibition of ICK at 1 uM | 6 | ALA1165965 | single protein format | Scientific Literature | ||
5. | ALA1174452 | Binding | Inhibition of ICK at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
6. | ALA1244868 | Binding | Binding affinity to ICK | 7 | ALA1240346 | single protein format | Scientific Literature | ||
7. | ALA1786945 | Binding | Inhibition of LCK2 | 1 | ALA1781905 | single protein format | Scientific Literature | ||
8. | ALA1826209 | Binding | Activity of ICK kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
9. | ALA4351893 | Binding | Inhibition of recombinant human ICK (1 to 312 residues) at 10 uM using RRRFRPASPLRGPPK as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting method | Homo sapiens | 1 | ALA4350961 | single protein format | Scientific Literature | |
10. | ALA4352421 | Binding | Inhibition of human LCK2 at 10 uM using MBP as substrate in presence of [gamma-33P]-ATP | Homo sapiens | 1 | ALA4350963 | single protein format | Scientific Literature | |
11. | ALA4357924 | Binding | Binding affinity to wild-type human partial length ICK (M1 to P314 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4354843 | assay format | Scientific Literature | |
12. | ALA1908787 | Binding | Binding constant for ICK kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
13. | ALA2211079 | Binding | Inhibition of ICK assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
14. | ALA3991734 | Binding | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 217 | ALA3991601 | subcellular format | Kuster lab chemical proteomics drug profiling | |
15. | ALA4025177 | Binding | Inhibition of wild-type human partial length ICK (M1 to P314 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
16. | ALA4043988 | Binding | Inhibition of wild-type human partial length ICK (M1 to P314 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
17. | ALA4048338 | Binding | Inhibition of partial length wild type human ICK expressed in mammalian expression system at 0.5 uM by KINOMEscan method relative to control | Homo sapiens | 1 | ALA4043283 | assay format | Scientific Literature | |
18. | ALA4054961 | Binding | Inhibition of wild-type human partial length ICK (M1 to P314 residues) expressed in mammalian expression system assessed as residual activity at 50 nM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4052645 | assay format | Scientific Literature | |
19. | ALA4145829 | Binding | Inhibition of ICK (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA4145442 | single protein format | Scientific Literature | |
20. | ALA4145881 | Binding | Inhibition of ICK (unknown origin) | Homo sapiens | 1 | ALA4145442 | single protein format | Scientific Literature |