| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA712301 | B | Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase) | Escherichia coli | 40 | single protein format | Scientific Literature | ||
| 2. | ALA870123 | B | Inhibition of Escherichia coli MTAN | Escherichia coli | 1 | single protein format | Scientific Literature | ||
| 3. | ALA931724 | B | Inhibition of Escherichia coli MTAN | Escherichia coli | 3 | single protein format | Scientific Literature | ||
| 4. | ALA1244617 | B | Inhibition of Escherichia coli O157:H7 EDL933 MTAN-mediated autoinducer-2 production assessed as inhibition of light induction in quorum-sensing Vibrio harveyi BB120 by luminescence induction assay | Escherichia coli O157:H7 | 2 | single protein format | Scientific Literature | ||
| 5. | ALA1244618 | B | Inhibition of Escherichia coli O157:H7 EDL933 MTAN-mediated autoinducer-2 production assessed as inhibition of light induction in quorum-sensing Vibrio harveyi BB120 at 4 times IC50 by luminescence induction assay relative to control | Escherichia coli O157:H7 | 1 | single protein format | Scientific Literature | ||
| 6. | ALA1244622 | B | Inhibition of MTAN in Escherichia coli O157:H7 EDL933 MTAN-mediated autoinducer-2 production assessed as inhibition of light induction in quorum-sensing Vibrio harveyi BB170 at 2.5 uM by luminescence induction assay relative to control | Escherichia coli O157:H7 | 1 | single protein format | Scientific Literature | ||
| 7. | ALA1244623 | B | Inhibition of MTAN in Escherichia coli O157:H7 EDL933 MTAN-mediated autoinducer-2 production assessed as inhibition of light induction in quorum-sensing Vibrio harveyi BB170 at 1 uM by luminescence induction assay relative to control | Escherichia coli O157:H7 | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3606937 | B | Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate by xanthine oxidase coupling enzyme assay | Escherichia coli | 2 | assay format | Scientific Literature | ||
| 9. | ALA3607078 | B | Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex by xanthine oxidase coupling enzyme assay | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 10. | ALA3607079 | B | Binding affinity to recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 at 225 uM by isothermal titration calorimetry | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 11. | ALA3755981 | A | Prodrug activation assessed as recombinant Escherichia coli SAH/MTA hydrolase-mediated compound cleavage at 100 uM by reverse phase HPLC analysis | Escherichia coli | 5 | single protein format | Scientific Literature |
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