| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2318154 | B | Ratio of 10074-G5 IC50 to compound IC50 for inhibition of recombinant His6-tagged c-Myc bHLH-ZIP domain (353 to 437 amino acid residues) (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA2318156 | B | Inhibition of recombinant His6-tagged c-Myc bHLH-ZIP domain (353 to 437 amino acid residues) (unknown origin) assessed as disruption of Myc-Max dimerization by electrophoretic mobility shift assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 3. | ALA2318157 | B | Inhibition of recombinant His6-tagged c-Myc bHLH-ZIP domain (353 to 437 amino acid residues) (unknown origin) assessed as disruption of Myc-Max dimerization at 100 uM by electrophoretic mobility shift assay relative to control | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 4. | ALA2318158 | B | Binding affinity to human c-Myc bHLH-ZIP domain (353 to 437 amino acid residues) expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA2353442 | B | Inhibition of Myc signaling pathway in human HeLa cells assessed as inhibition of PMA induced luciferase at 100 uM treated 30 mins before induction | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA2353443 | B | Inhibition of Myc signaling pathway in human HeLa cells assessed as measured as lowest concentration required 50 to 60 % inhibition of PMA induced luciferase treated 30 mins before induction | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA2353444 | B | Inhibition of Myc signaling pathway in human HeLa cells assessed as inhibition of PMA induced luciferase treated 30 mins before induction | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA3223392 | B | Inhibition of c-MYC in human HL60 cells by chemiluminescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3223396 | B | Binding affinity to c-MYC (353 to 437) (unknown origin) by fluorescence polarization assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 10. | ALA3428720 | B | Binding affinity to human recombinant 15N labeled c-Myc monomer assessed as chemical shift up to 100 uM by NMR spectroscopy | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA3428883 | B | Inhibition of wild type c-Myc binding site (unknown origin) expressed in human HeLa cells assessed as inhibition of luciferase after 6 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3869025 | B | Inhibition of C-MYC in human Jurkat cells assessed as decrease in LDHA level at EC50 measured after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3869026 | B | Inhibition of C-MYC in human NALM6 cells assessed as decrease in LDHA level at EC50 measured after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3869027 | B | Inhibition of C-MYC in human REH cells assessed as decrease in LDHA level at EC50 measured after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3869028 | B | Inhibition of C-MYC in human Jurkat cells assessed as decrease in GLS level at EC50 measured after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3869029 | B | Inhibition of C-MYC in human NALM6 cells assessed as decrease in GLS level at EC50 measured after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3869030 | B | Inhibition of C-MYC in human REH cells assessed as decrease in GLS level at EC50 measured after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3869031 | B | Inhibition of C-MYC in human Jurkat cells assessed as decrease in PKM2 level at EC50 measured after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3869032 | B | Inhibition of C-MYC in human NALM6 cells assessed as decrease in PKM2 level at EC50 measured after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3869033 | B | Inhibition of C-MYC in human REH cells assessed as decrease in PKM2 level at EC50 measured after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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