# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1226366 | B | Binding affinity to SAP130 assessed as inhibition of radio labeled beta-globin pre-mRNA splicing after 1 hr by autoradiography | 1 | ALA1221204 | single protein format | Scientific Literature | ||
2. | ALA1226367 | B | Binding affinity to SAP130 assessed as inhibition of radio labeled IgM pre-mRNA splicing after 1 hr by autoradiography | 1 | ALA1221204 | single protein format | Scientific Literature | ||
3. | ALA1226368 | B | Binding affinity to SAP130 in human HeLa cells assessed as inhibition of FLAG-tagged beta globin splicing at 100 ng/ml after 12 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA1221204 | cell-based format | Scientific Literature | |
4. | ALA1226369 | B | Binding affinity to SAP130 in human HeLa cells assessed as inhibition of p27 mRNA splicing at 100 ng/ml after 6 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA1221204 | cell-based format | Scientific Literature | |
5. | ALA1226370 | B | Binding affinity to SAP130 in human HeLa cells assessed as inhibition of beta-tubulin mRNA splicing at 100 ng/ml after 6 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA1221204 | cell-based format | Scientific Literature | |
6. | ALA1226371 | B | Binding affinity to SAP130 in human HeLa cells assessed as inhibition of beta-actin mRNA splicing at 100 ng/ml after 6 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA1221204 | cell-based format | Scientific Literature | |
7. | ALA1226372 | B | Binding affinity to SAP130 in human HeLa cells assessed as inhibition of p27 pre-mRNA splicing between exon 1 and exon 2 at 10 mg/ml after 12 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA1221204 | cell-based format | Scientific Literature | |
8. | ALA1226373 | B | Binding affinity to SAP130 in human HeLa cells assessed as inhibition of p27 pre-mRNA splicing between exon 1 and intron 2 at 10 mg/ml after 12 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA1221204 | cell-based format | Scientific Literature | |
9. | ALA1226374 | B | Binding affinity to SAP130 in human HeLa cells assessed as inhibition of IkappaBalpha pre-mRNA splicing between exon 1 and exon 4 at 10 mg/ml after 12 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA1221204 | cell-based format | Scientific Literature | |
10. | ALA1243659 | B | Binding affinity to SAP130 in SAP130-targeting siRNA-treated human HeLa cells at 1 uM by fluorescent microscopy | Homo sapiens | 1 | ALA1240330 | cell-based format | Scientific Literature | |
11. | ALA1243661 | B | Displacement of photoaffinity/biotin-tagged chemical probes from SAP130 in human HeLa cells at 1.5 uM by immunoblotting | Homo sapiens | 4 | ALA1240330 | cell-based format | Scientific Literature | |
12. | ALA1243662 | B | Displacement of [3H]probe from SAP130 in human WiDr cells assessed as radioactive intensity at 500 nM after 1 hr by scintillation counting relative to control | Homo sapiens | 11 | ALA1240330 | cell-based format | Scientific Literature | |
13. | ALA1243663 | B | Displacement of [3H]probe from SAP130 in human WiDr cell immunoprecipitate sample assessed as radioactive intensity at 500 nM after 1 hr by scintillation counting relative to control | Homo sapiens | 11 | ALA1240330 | cell-based format | Scientific Literature | |
14. | ALA1243664 | B | Inhibition of SAP130-mediated splicing of BRD2 gene in human HeLa cells at 1 to 10000 nM by RT-PCR analysis | Homo sapiens | 1 | ALA1240330 | cell-based format | Scientific Literature | |
15. | ALA1243665 | B | Inhibition of SAP130-mediated splicing of RIOK3 gene in human HeLa cells at 1 to 10000 nM by RT-PCR analysis | Homo sapiens | 1 | ALA1240330 | cell-based format | Scientific Literature | |
16. | ALA1243666 | B | Displacement of [3H]probe from SAP130 in human WiDr cell immunoprecipitate sample assessed as radioactive intensity at 10 uM after 1 hr by scintillation counting | Homo sapiens | 1 | ALA1240330 | single protein format | Scientific Literature | |
17. | ALA1243667 | B | Inhibition of SAP130-mediated splicing of DNAJB1 gene in human HeLa cells at 1 uM after 4 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA1240330 | cell-based format | Scientific Literature | |
18. | ALA1243668 | B | Inhibition of SAP130-mediated splicing of BRD2 gene in human HeLa cells at 1 uM after 4 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA1240330 | cell-based format | Scientific Literature | |
19. | ALA1243669 | B | Inhibition of SAP130-mediated splicing of RIOK3 gene in human HeLa cells at 1 uM after 4 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA1240330 | cell-based format | Scientific Literature | |
20. | ALA1243670 | B | Inhibition of SAP130-mediated splicing of DNAJB1 gene in human HeLa cells after 4 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA1240330 | cell-based format | Scientific Literature |