# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1244672 | B | Inhibition of Dusp5 | 1 | single protein format | Scientific Literature | |||
2. | ALA4417858 | B | Inhibition of GST-tagged full length DUSP5 (unknown origin) incubated for 90 mins in presence of Triton-X100 by pNPP phosphatase assay | Homo sapiens | 1 | single protein format | Patent Bioactivity Data | ||
3. | ALA4417859 | B | Inhibition of N-terminal hexa-histidine-tagged wild type DUSP5 phosphatase domain (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 90 mins in presence of Triton-X100 by pNPP phosphatase assay | Homo sapiens | 10 | assay format | Patent Bioactivity Data | ||
4. | ALA4417860 | B | Inhibition of N-terminal hexa-histidine-tagged wild type DUSP5 phosphatase domain (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 90 mins in absence of Triton-X100 by pNPP phosphatase assay | Homo sapiens | 1 | assay format | Patent Bioactivity Data | ||
5. | ALA4417861 | B | Binding affinity to N-terminal hexa-histidine-tagged and 15N-labeled DUSP5 C263S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) at 250 uM by 2D 1H-15N HSQC NMR assay | Homo sapiens | 1 | assay format | Patent Bioactivity Data | ||
6. | ALA4417862 | B | Competitive inhibition of N-terminal hexa-histidine-tagged wild type DUSP5 phosphatase domain (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 90 mins in presence of Triton-X100 by pNPP phosphatase assay | Homo sapiens | 1 | assay format | Patent Bioactivity Data | ||
7. | ALA4417863 | B | Binding affinity to N-terminal hexa-histidine-tagged and 15N-labeled DUSP5 C263S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) at 500 uM by 2D 1H-15N HSQC NMR assay | Homo sapiens | 1 | assay format | Patent Bioactivity Data | ||
8. | ALA4417864 | B | Inhibition of DUSP5 in HUVEC assessed as reduction in phosphorylated ERK levels at 0.1 to 100 uM incubated for 2 hrs by SDS-PAGE based assay | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
9. | ALA4417865 | B | Inhibition of full length DUSP5 (unknown origin) assessed as reduction in de-phosphorylation of GST-tagged recombinant phosphorylated ERK2 incubated for 15 mins by SDS-PAGE based immunoblot assay | Homo sapiens | 3 | single protein format | Patent Bioactivity Data | ||
10. | ALA4417866 | B | Potency index, ratio of IC50 for NTS to IC50 for test compound for inhibition of full length DUSP5 (unknown origin) assessed as reduction in de-phosphorylation of GST-tagged recombinant phosphorylated ERK2 incubated for 15 mins by SDS-PAGE based immunoblot assay | Homo sapiens | 1 | single protein format | Patent Bioactivity Data |