# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1261569 | B | Inhibition of eIF2alpha autophosphorylation in human MCF7 cells | Homo sapiens | 2 | ALA1255220 | cell-based format | Scientific Literature | |
2. | ALA1261570 | B | Inhibition of eIF2alpha autophosphorylation in human A2780 cells | Homo sapiens | 2 | ALA1255220 | cell-based format | Scientific Literature | |
3. | ALA1826796 | B | Induction of eIF2alpha phosphorylation in human MCF7 cells at 3 times IC50 after 36 hrs by Western blot analysis | Homo sapiens | 3 | ALA1821645 | cell-based format | Scientific Literature | |
4. | ALA3242916 | B | Induction of eIF2-alpha phosphorylation in human A549 cells by immunoblot analysis | Homo sapiens | 1 | ALA3232734 | cell-based format | Scientific Literature | |
5. | ALA4146668 | B | Inhibition of H2O2-induced eIF2alpha phosphorylation in human SH-SY5Y cells at 1 uM | Homo sapiens | 5 | ALA4145470 | cell-based format | Scientific Literature | |
6. | ALA4146669 | B | Inhibition of H2O2-induced eIF2alpha phosphorylation in human SH-SY5Y cells at 0.1 uM | Homo sapiens | 9 | ALA4145470 | cell-based format | Scientific Literature | |
7. | ALA4390760 | B | Induction of EIF2alpha phosphorylation in human U87MG cells at 20 uM measured after 2 hrs by Western blot analysis | Homo sapiens | 6 | ALA4390639 | cell-based format | Scientific Literature | |
8. | ALA4390761 | B | Induction of EIF2alpha phosphorylation in human U87MG cells at 10 ug/ml measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA4390639 | cell-based format | Scientific Literature | |
9. | ALA4390762 | B | Induction of EIF2alpha phosphorylation in human U87MG cells at 1 uM measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA4390639 | cell-based format | Scientific Literature | |
10. | ALA4390765 | B | Induction of EIF2alpha phosphorylation in human A172 cells at 20 uM measured after 2 hrs by Western blot analysis | Homo sapiens | 6 | ALA4390639 | cell-based format | Scientific Literature | |
11. | ALA4390766 | B | Induction of EIF2alpha phosphorylation in human A172 cells at 10 ug/ml measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA4390639 | cell-based format | Scientific Literature | |
12. | ALA4390767 | B | Induction of EIF2alpha phosphorylation in human A172 cells at 1 uM measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA4390639 | cell-based format | Scientific Literature | |
13. | ALA4707852 | B | Activation of eIF2alpha (unknown origin) assessed as fold stimulation ATF-4 surrogate eIF2alpha phosphorylation at 1.25 uM cell based Dual luciferase reporter assay | Homo sapiens | 24 | ALA4706490 | cell-based format | Scientific Literature | |
14. | ALA4707853 | B | Activation of eIF2alpha (unknown origin) assessed as fold stimulation ATF-4 surrogate eIF2alpha phosphorylation at 5 uM cell based Dual luciferase reporter assay | Homo sapiens | 24 | ALA4706490 | cell-based format | Scientific Literature | |
15. | ALA4707855 | B | Activation of eIF2alpha in human CRL-2813 cells assessed as eIF2alpha phosphorylation at 5 uM measured after 2 hrs Western blot analysis | Homo sapiens | 7 | ALA4706490 | cell-based format | Scientific Literature | |
16. | ALA4707856 | B | Activation of eIF2alpha in human CRL-2813 cells assessed as increase in CHOP expression at 5 uM measured after 8 hrs Western blot analysis | Homo sapiens | 7 | ALA4706490 | cell-based format | Scientific Literature | |
17. | ALA4707857 | B | Activation of eIF2alpha in human CRL-2813 cells assessed as decrease in cyclin D1 expression at 5 uM measured after 8 hrs Western blot analysis | Homo sapiens | 7 | ALA4706490 | cell-based format | Scientific Literature | |
18. | ALA4822226 | B | Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay | Homo sapiens | 30 | ALA4819104 | single protein format | Scientific Literature |