# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1267288 | B | Inhibition of GOAT mediated Wnt3a pathway activity in mouse L cell expressing Wnt3a assessed as decreased firefly luciferase reporter expression at 0.25 uM to 1 uM | Mus musculus | 1 | ALA1255380 | cell-based format | Scientific Literature | |
2. | ALA4482489 | B | Inhibition of mouse GOAT expressed in HEK293FT cells co-expressing pre-proghrelin assessed as reduction in ghrelin octanoylation up to 1 uM incubated for 24 hrs by ELISA | Mus musculus | 1 | ALA4482308 | cell-based format | Patent Bioactivity Data | |
3. | ALA4482490 | B | Inhibition of mouse GOAT expressed in HEK293FT cells co-expressing pre-proghrelin assessed as reduction in ghrelin octanoylation incubated for 24 hrs by ELISA | Mus musculus | 2 | ALA4482308 | cell-based format | Patent Bioactivity Data | |
4. | ALA4482677 | B | Inhibition of His10-tagged mouse GOAT expressed in baculovirus infected Sf9 cells assessed as reduction in specific acyl transfer from tritiated-octanoyl CoA to recombinant His-tagged pro-ghrelin at 500 uM | Mus musculus | 4 | ALA4482314 | cell-based format | Patent Bioactivity Data | |
5. | ALA4482678 | B | Inhibition of His10-tagged mouse GOAT expressed in baculovirus infected Sf9 cells assessed as reduction in specific acyl transfer from tritiated-octanoyl CoA to recombinant His-tagged pro-ghrelin at <500 uM | Mus musculus | 2 | ALA4482314 | cell-based format | Patent Bioactivity Data | |
6. | ALA4482679 | B | Inhibition of His10-tagged mouse GOAT expressed in baculovirus infected Sf9 cells assessed as reduction in specific acyl transfer from tritiated-octanoyl CoA to recombinant His-tagged pro-ghrelin | Mus musculus | 12 | ALA4482314 | cell-based format | Patent Bioactivity Data | |
7. | ALA4482680 | B | Inhibition of His10-tagged mouse GOAT expressed in baculovirus infected Sf9 cells assessed as reduction in specific acyl transfer from tritiated-octanoyl CoA to recombinant His-tagged pro-ghrelin at 100 uM | Mus musculus | 4 | ALA4482314 | cell-based format | Patent Bioactivity Data | |
8. | ALA4673667 | B | Inhibition of mouse GOAT expressed in baculovirus infected sf9 insect cell microsomes using biotinylated des-acyl ghrelin and octanoyl-CoA -CoA as substrate incubated for 15 mins by HTRF assay | Mus musculus | 2 | ALA4673189 | microsome format | Scientific Literature | |
9. | ALA4673669 | B | Antagonist activity at mouse GOAT expressed in baculovirus infected sf9 insect cell membrane using ghrelin(1 to 5) pentapeptide as substrate preincubated for 5 mins followed by Palmitoyl-CoA and n-octynoyl-CoA addition and measured after 5 mins by amplex red/H2O2 reagent-based fluorescence method | Mus musculus | 2 | ALA4673189 | cell membrane format | Scientific Literature | |
10. | ALA4673670 | B | Inhibition of N-terminal His10-tagged mouse GOAT expressed in baculovirus infected sf9 insect cell membrane using proghrelin-His8 and [3H]octanoyl CoA as substrate by scintillation counting method | Mus musculus | 6 | ALA4673189 | cell membrane format | Scientific Literature |