# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1056198 | B | Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2X assessed as residual activity at 1000 uM preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)propionylsulfanyl]acetic acid and 5,5'-dithiobis(2-nitrobenzoic acid) | Streptococcus pneumoniae R6 | 19 | ALA1155217 | single protein format | Scientific Literature | |
2. | ALA1056939 | B | Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2X assessed as residual activity at 100 uM preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)propionylsulfanyl]acetic acid and 5,5'-dithiobis(2-nitrobenzoic acid) | Streptococcus pneumoniae R6 | 2 | ALA1155217 | single protein format | Scientific Literature | |
3. | ALA1055310 | B | Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2X assessed as residual activity at 500 uM preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)propionylsulfanyl]acetic acid and 5,5'-dithiobis(2-nitrobenzoic acid) | Streptococcus pneumoniae R6 | 3 | ALA1155217 | single protein format | Scientific Literature | |
4. | ALA1053623 | B | Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2X preincubated for 1 hr before addition of substrate (R)-[2-(benzoylamino)propionylsulfanyl]acetic acid | Streptococcus pneumoniae R6 | 44 | ALA1155224 | single protein format | Scientific Literature | |
5. | ALA1266813 | B | Binding affinity to PBP 2x in Streptococcus pneumoniae R6 at 1.1 ng/ml to 1.1 ug /ml | Streptococcus pneumoniae R6 | 1 | ALA1255255 | single protein format | Scientific Literature | |
6. | ALA2039463 | B | Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Streptococcus pneumoniae R6 | 8 | ALA2034818 | single protein format | Scientific Literature | |
7. | ALA2039464 | B | Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate assessed as residual activity at 1 mM incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Streptococcus pneumoniae R6 | 18 | ALA2034818 | single protein format | Scientific Literature | |
8. | ALA2039465 | B | Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate assessed as residual activity at 1 mM incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry in presence of triton X 100 | Streptococcus pneumoniae R6 | 4 | ALA2034818 | single protein format | Scientific Literature |