| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA953475 | B | Inhibition of Escherichia coli AmpC assessed as induction of protein unfolding measured by trypsin mediated degradation of compound-AmpC enzyme complex at 100 uM after 4 hrs by gel electrophoresis | Escherichia coli | 2 | ALA1153954 | single protein format | Scientific Literature | |
| 2. | ALA953476 | B | Inhibition of Escherichia coli AmpC assessed as induction of protein unfolding measured by trypsin mediated degradation of compound-AmpC enzyme complex at 250 uM after 15 mins by gel electrophoresis | Escherichia coli | 3 | ALA1153954 | single protein format | Scientific Literature | |
| 3. | ALA960994 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 42-56 amino acid sequence after 10 mins by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 4. | ALA960995 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 8-18 amino acid sequence after 10 mins by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 5. | ALA960996 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 105-128 amino acid sequence after 10 mins by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 6. | ALA960997 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 109-128 amino acid sequence after 10 mins by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 7. | ALA960998 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 132-146 amino acid sequence after 10 mins by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 8. | ALA961772 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 243-250 amino acid sequence after 10 mins by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 9. | ALA961773 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 271-289 amino acid sequence after 10 mins by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 10. | ALA961774 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 291-322 amino acid sequence after 10 mins by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 11. | ALA961775 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 323-332 amino acid sequence after 10 mins by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 12. | ALA961776 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 336-350 amino acid sequence after 10 mins by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 13. | ALA961777 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 8-18 amino acid sequence after 1 hr by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 14. | ALA961778 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 42-56 amino acid sequence after 1 hr by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 15. | ALA961779 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 105-128 amino acid sequence after 1 hr by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 16. | ALA961780 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 109-128 amino acid sequence after 1 hr by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 17. | ALA961781 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 132-146 amino acid sequence after 1 hr by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 18. | ALA961782 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 271-289 amino acid sequence after 1 hr by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 19. | ALA961783 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 291-322 amino acid sequence after 1 hr by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature | |
| 20. | ALA961784 | B | Aggregation based inhibition of Escherichia coli AmpC assessed as increase in deuteration of AmpC peptide fragment spanning 323-332 amino acid sequence after 1 hr by hydrogen-deuterium exchange mass spectrometry relative to control | Escherichia coli | 1 | ALA1153954 | single protein format | Scientific Literature |
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