| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1267177 | B | Increase in porcn levels in mouse L cell expressing Wnt and STF | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA1267178 | B | Effect on porcn Endoplasmic reticulum localization in mouse L cell expressing Wnt and STF | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA1267184 | B | Inhibition of porcn-mediated Wnt5A palmitoylation in mouse L cell expressing Wnt5A and STF by detergent solubility fractionation assessed as [3H]palmitate incorporation at 2 uM by autoradiography method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA2330985 | B | Inhibition of porcupine in E11.5 mouse embryo kidney assessed as inhibition of Wnt-mediated branching morphogenesis at 10 to 50 nM measured every 24 hrs by fluorescent stereoscopic analysis relative to control | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 5. | ALA2330993 | B | Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay | Mus musculus | 63 | cell-based format | Scientific Literature | ||
| 6. | ALA3635402 | B | Inhibition of mouse porcupine expressed in human HT1080 cells assessed as reduction in beta catenin reporter activity using firefly luciferase substrate STF reporter assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3861541 | B | Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells after 48 hrs by Super-top flash reporter gene assay | Mus musculus | 26 | cell-based format | Scientific Literature | ||
| 8. | ALA3870974 | B | Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay | Mus musculus | 40 | assay format | Scientific Literature | ||
| 9. | ALA3870977 | B | Inhibition of porcupine-mediated Wnt signaling in mouse L-cells at 1 uM after 24 hrs by springerImage-Topflash reporter assay | Mus musculus | 1 | assay format | Scientific Literature | ||
| 10. | ALA4000306 | B | Inhibition of mouse PORCN expressed in human HT1080 cells coexpressing Wnt/beta-catenin assessed as decrease in beta-catenin-mediated transcriptional activity at 0.2 to 625 nM after 24 hrs in presence of Wnt3a by luciferase reporter gene assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4040045 | B | Inhibition of mouse PORCN expressed in human HT1080 cells coexpressing Wnt/beta-catenin assessed as decrease in beta-catenin-mediated transcriptional activity at 1 to 1000 nM after 24 hrs in presence of Wnt3a by luciferase reporter gene assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4197842 | B | Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash reporter gene assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 13. | ALA4427408 | B | Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by luminescence assay | Mus musculus | 22 | cell-based format | Scientific Literature |
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