# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3635402 | Binding | Inhibition of mouse porcupine expressed in human HT1080 cells assessed as reduction in beta catenin reporter activity using firefly luciferase substrate STF reporter assay | Mus musculus | 1 | ALA3632565 | cell-based format | Scientific Literature | |
2. | ALA1267177 | Binding | Increase in porcn levels in mouse L cell expressing Wnt and STF | Mus musculus | 1 | ALA1255380 | cell-based format | Scientific Literature | |
3. | ALA1267178 | Binding | Effect on porcn Endoplasmic reticulum localization in mouse L cell expressing Wnt and STF | Mus musculus | 1 | ALA1255380 | cell-based format | Scientific Literature | |
4. | ALA1267184 | Binding | Inhibition of porcn-mediated Wnt5A palmitoylation in mouse L cell expressing Wnt5A and STF by detergent solubility fractionation assessed as [3H]palmitate incorporation at 2 uM by autoradiography method | Mus musculus | 1 | ALA1255380 | cell-based format | Scientific Literature | |
5. | ALA2330985 | Binding | Inhibition of porcupine in E11.5 mouse embryo kidney assessed as inhibition of Wnt-mediated branching morphogenesis at 10 to 50 nM measured every 24 hrs by fluorescent stereoscopic analysis relative to control | Mus musculus | 1 | ALA2321875 | single protein format | Scientific Literature | |
6. | ALA2330993 | Binding | Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay | Mus musculus | 63 | ALA2321875 | cell-based format | Scientific Literature | |
7. | ALA3861541 | Binding | Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells after 48 hrs by Super-top flash reporter gene assay | Mus musculus | 26 | ALA3860088 | cell-based format | Scientific Literature | |
8. | ALA3870974 | Binding | Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay | Mus musculus | 40 | ALA3870337 | assay format | Scientific Literature | |
9. | ALA3870977 | Binding | Inhibition of porcupine-mediated Wnt signaling in mouse L-cells at 1 uM after 24 hrs by springerImage-Topflash reporter assay | Mus musculus | 1 | ALA3870337 | assay format | Scientific Literature | |
10. | ALA4000306 | Binding | Inhibition of mouse PORCN expressed in human HT1080 cells coexpressing Wnt/beta-catenin assessed as decrease in beta-catenin-mediated transcriptional activity at 0.2 to 625 nM after 24 hrs in presence of Wnt3a by luciferase reporter gene assay | Mus musculus | 1 | ALA4000145 | cell-based format | Scientific Literature | |
11. | ALA4040045 | Binding | Inhibition of mouse PORCN expressed in human HT1080 cells coexpressing Wnt/beta-catenin assessed as decrease in beta-catenin-mediated transcriptional activity at 1 to 1000 nM after 24 hrs in presence of Wnt3a by luciferase reporter gene assay | Mus musculus | 1 | ALA4038310 | cell-based format | Scientific Literature | |
12. | ALA4197842 | Binding | Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash reporter gene assay | Mus musculus | 6 | ALA4196048 | cell-based format | Scientific Literature | |
13. | ALA4427408 | Binding | Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by luminescence assay | Mus musculus | 22 | ALA4425166 | cell-based format | Scientific Literature |