# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1799484 | B | Inhibition of mTOR-dependent S6K phosphorylation at T389 residue in MEF cells | Mus musculus | 15 | cell-based format | Scientific Literature | ||
2. | ALA1261685 | B | Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblotting | Mus musculus | 33 | single protein format | Scientific Literature | ||
3. | ALA1768754 | B | Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblotting | Mus musculus | 26 | single protein format | Scientific Literature | ||
4. | ALA3882647 | B | Inhibition of mTOR in mouse N9 cells assessed as decrease in phospho-p70S6K by Western blot analysis | Mus musculus | 2 | cell-based format | Patent Bioactivity Data | ||
5. | ALA3882648 | B | Inhibition of mTOR in mouse N9 cells assessed as decrease in phospho-4E-BP by Western blot analysis | Mus musculus | 2 | cell-based format | Patent Bioactivity Data | ||
6. | ALA3882665 | B | Inhibition of mTOR in TFEB knock-down mouse N9 cells assessed as increase in lysosome biogenesis by measuring Lyso tracker fluorescence measured after 8 hrs by Lyso tracker staining based flow cytometry | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
7. | ALA3882669 | B | Inhibition of mTOR in mouse N9 cells assessed as effect on autophagosome formation by measuring p62 levels in presence of squalene synthase inhibitor CP-340868 | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
8. | ALA3882670 | B | Inhibition of mTOR in mouse N9 cells assessed as effect on autophagosome formation by measuring p62 levels in presence of HMG CoA reductase inhibitor lovastatin | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
9. | ALA3882671 | B | Inhibition of mTOR1 in wild type mouse microglia | Mus musculus | 1 | single protein format | Patent Bioactivity Data | ||
10. | ALA3882672 | B | Inhibition of mTOR1 in ACAT1 knockout mouse microglia | Mus musculus | 1 | single protein format | Patent Bioactivity Data | ||
11. | ALA3882673 | B | Inhibition of mTOR in mouse N9 cells assessed as effect on lysosome biogenesis by measuring cellular acidic compartments in presence of PI3-kinase inhibitor 3-methyladenine | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
12. | ALA3882674 | B | Inhibition of mTOR in AtgS knock-down mouse N9 cells assessed as autophagosome formation by measuring TFEB mRNA expression levels | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
13. | ALA3882675 | B | Inhibition of mTOR in AtgS knock-down mouse N9 cells assessed as autophagosome formation by measuring AtgS protein level by Western blot analysis relative to control | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
14. | ALA3882676 | B | Inhibition of mTOR in AtgS knock-down mouse N9 cells assessed as autophagosome formation by measuring LC3-2 level by Western blot analysis | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
15. | ALA3882677 | B | Inhibition of mTOR in AtgS knock-down mouse N9 cells assessed as autophagosome formation by measuring LC3 puncta by Western blot analysis | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
16. | ALA3882678 | B | Inhibition of mTOR in TFEB knock-down mouse N9 cells assessed as autophagosome formation by measuring LC3-2 levels | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
17. | ALA4381555 | B | Inhibition of mTOR in mouse TSC1-/- MEF cells assessed as inhibition of S6 Ser240/244 phosphorylation incubated for 2 hrs by fluorescence based assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
18. | ALA4381568 | B | Inhibition of mTOR in mouse MEF cells harboring TSC1 deletion mutant assessed as reduction in PS6 phosphorylation incuabted for 2 hrs alexa fluor 594 and Hoechst staining based fluorescence assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
19. | ALA4381606 | B | Inhibition of mTOR in mouse primary cortical neuron harboring TSC1 deletion mutant assessed as reduction in PS6 phosphorylation incubated for 4 hrs by Western blot analysis | Mus musculus | 1 | single protein format | Scientific Literature | ||
20. | ALA4434258 | B | Inhibition of mTOR in mouse TSC1-/- MEF cells assessed as inhibition of S6 Ser240/244 phosphorylation incubated for 2 hrs by fluorescence based assay | Mus musculus | 6 | cell-based format | Scientific Literature |