| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2050394 | B | Inhibition of His6X-tagged PRMT6 expressed in Escherichia coli BL21(DE3) cells using [14C]-S-adenosyl-L-methionine and histone H4 peptide after 8 mins by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 2. | ALA1273736 | B | Inhibition of His6x-tagged PRMT6-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H3(1-31) peptide and [14C]-SAM by scintillation counting | 1 | assay format | Scientific Literature | |||
| 3. | ALA2182455 | B | Inhibition of recombinant PRMT6 using histone H3 as substrate at 50 uM and [3H]-SAM after 90 mins by scintillation counting | 2 | single protein format | Scientific Literature | |||
| 4. | ALA5138948 | B | Inhibition of human full length recombinant GST-tagged PRMT6 (2 to 375 residues) using GST-GAR as substrate incubated for 20 mins in presence of [3H]-SAM by radioisotope-based filter assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 5. | ALA3111897 | B | Inhibition of PRMT6 (unknown origin)-mediated incorporation of methyl group from [3H]-SAM into peptide substrate up to 50 uM by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA3226872 | B | Activity at 100 to 400 nM of PRMT6 (unknown origin) assessed as increase of Vmax up to 200 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3226873 | B | Activity at 50 to 800 nM of PRMT6 (unknown origin) assessed as increase of Vmax up to 200 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3226874 | B | Activity at 50 to 800 nM of PRMT6 (unknown origin) assessed as increase of Km up to 200 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA3226875 | B | Inhibition of 50 to 100 nM of PRMT6 (unknown origin) up to 200 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA3226876 | B | Activity at 50 to 100 nM of PRMT6 (unknown origin) up to 200 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA3226882 | B | Activity at 400 nM of PRMT6 (unknown origin) using histone H3 tail peptide | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA3226884 | B | Activity at PRMT6 (unknown origin) at 100 uM using => 5 uM of AdoMet | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA3226885 | B | Inhibition of PRMT6 (unknown origin) using AdoMet by Michaelis-Menten equation analysis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 14. | ALA3226887 | B | Activity at PRMT6 (unknown origin) up to 40 uM using AdoMet by Michaelis-Menten equation analysis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 15. | ALA3226890 | B | Activity at PRMT6 (unknown origin) using AdoMet assessed as formation of MMA and aDMA at 0.25 to 200 uM after 60 to 120 mins by LC-MS/MS analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 16. | ALA3226893 | B | Activity at PRMT6 (unknown origin) using [methyl-14C]AdoMet at 0.25 to 200 uM after 60 to 120 mins by tricine gel electrophoresis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 17. | ALA3225386 | B | Activity at PRMT6 (unknown origin) assessed as methylation of substituted arginines by LC-MS/MS analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 18. | ALA3239254 | B | Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 19. | ALA3578942 | B | Inhibition of PRMT6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA3591482 | B | Inhibition of FLAG and hexa-histidine tagged full-length human PRMT6 expressed in HEK293F cells pre-incubated for 30 mins before addition of a [3H]SAM and peptide mix | Homo sapiens | 21 | cell-based format | Scientific Literature |
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