# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA691841 | B | Inhibition of the specific binding of [3H](R)-alpha-methylhistamine ([3H]RMHA) to Histamine H3 receptor in rat brain membranes at 10e-8 M | 6 | cell membrane format | Scientific Literature | |||
2. | ALA696451 | B | Binding affinity of compound towards rat histamine H4 receptor | 2 | single protein format | Scientific Literature | |||
3. | ALA948407 | F | Antagonist activity at rat histamine H4 receptor assessed as inhibition of histamine-induced intracellular calcium level by FLIPR | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
4. | ALA948409 | F | Antagonist activity at rat histamine H4 receptor assessed as inhibition of histamine-induced [35S]GTPgamma binding | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
5. | ALA948411 | B | Displacement of [3H]histamine from rat histamine H4 receptor expressed in HEK293 cells by liquid scintillation counting | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
6. | ALA986303 | F | Antagonist activity at rat histamine H4 receptor expressed in HEK293 cells assessed as inhibition of histamine-induced intracellular calcium elevation by FLIPR assay | Rattus norvegicus | 18 | cell-based format | Scientific Literature | ||
7. | ALA986304 | F | Antagonist activity at rat histamine H4 receptor expressed in HEK293 cells assessed as inhibition of histamine-induced intracellular calcium elevation by FLIPR assay relative to histamine | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
8. | ALA986308 | B | Displacement of [3H]histamine from rat histamine H4 receptor expressed in HEK293 cells | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
9. | ALA1027435 | F | Antagonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay | Rattus norvegicus | 12 | cell-based format | Scientific Literature | ||
10. | ALA1027436 | F | Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay | Rattus norvegicus | 77 | cell-based format | Scientific Literature | ||
11. | ALA1027437 | F | Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay relative to histamine | Rattus norvegicus | 76 | cell-based format | Scientific Literature | ||
12. | ALA1028284 | B | Displacement of [3H]histamine from rat histamine H4 receptor expressed in HEK293 cells | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
13. | ALA1028292 | F | Antagonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein by GTPgammaS assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
14. | ALA1028293 | F | Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein by GTPgammaS assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
15. | ALA1028294 | F | Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein by GTPgammaS assay relative to histamine | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
16. | ALA960691 | B | Binding affinity to rat histamine H4 receptor | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
17. | ALA960692 | F | Antagonist activity at rat histamine H4 receptor | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
18. | ALA1074193 | B | Binding affinity to rat histamine H4 receptor | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
19. | ALA1116870 | F | Antagonist activity at rat histamine H4 receptor assessed as decrease in intracellular calcium by FLIPR | Rattus norvegicus | 38 | cell-based format | Scientific Literature | ||
20. | ALA1116877 | B | Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation counting | Rattus norvegicus | 5 | single protein format | Scientific Literature |