# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA691841 | B | Inhibition of the specific binding of [3H](R)-alpha-methylhistamine ([3H]RMHA) to Histamine H3 receptor in rat brain membranes at 10e-8 M | 6 | ALA1135006 | cell membrane format | Scientific Literature | ||
2. | ALA696451 | B | Binding affinity of compound towards rat histamine H4 receptor | 2 | ALA1145077 | single protein format | Scientific Literature | ||
3. | ALA948407 | F | Antagonist activity at rat histamine H4 receptor assessed as inhibition of histamine-induced intracellular calcium level by FLIPR | Rattus norvegicus | 2 | ALA1140203 | cell-based format | Scientific Literature | |
4. | ALA948409 | F | Antagonist activity at rat histamine H4 receptor assessed as inhibition of histamine-induced [35S]GTPgamma binding | Rattus norvegicus | 1 | ALA1140203 | assay format | Scientific Literature | |
5. | ALA948411 | B | Displacement of [3H]histamine from rat histamine H4 receptor expressed in HEK293 cells by liquid scintillation counting | Rattus norvegicus | 2 | ALA1140203 | cell-based format | Scientific Literature | |
6. | ALA986303 | F | Antagonist activity at rat histamine H4 receptor expressed in HEK293 cells assessed as inhibition of histamine-induced intracellular calcium elevation by FLIPR assay | Rattus norvegicus | 18 | ALA1140165 | cell-based format | Scientific Literature | |
7. | ALA986304 | F | Antagonist activity at rat histamine H4 receptor expressed in HEK293 cells assessed as inhibition of histamine-induced intracellular calcium elevation by FLIPR assay relative to histamine | Rattus norvegicus | 6 | ALA1140165 | cell-based format | Scientific Literature | |
8. | ALA986308 | B | Displacement of [3H]histamine from rat histamine H4 receptor expressed in HEK293 cells | Rattus norvegicus | 14 | ALA1140165 | cell-based format | Scientific Literature | |
9. | ALA1027435 | F | Antagonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay | Rattus norvegicus | 12 | ALA1140148 | cell-based format | Scientific Literature | |
10. | ALA1027436 | F | Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay | Rattus norvegicus | 77 | ALA1140148 | cell-based format | Scientific Literature | |
11. | ALA1027437 | F | Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay relative to histamine | Rattus norvegicus | 76 | ALA1140148 | cell-based format | Scientific Literature | |
12. | ALA1028284 | B | Displacement of [3H]histamine from rat histamine H4 receptor expressed in HEK293 cells | Rattus norvegicus | 3 | ALA1140148 | cell-based format | Scientific Literature | |
13. | ALA1028292 | F | Antagonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein by GTPgammaS assay | Rattus norvegicus | 2 | ALA1140148 | cell-based format | Scientific Literature | |
14. | ALA1028293 | F | Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein by GTPgammaS assay | Rattus norvegicus | 2 | ALA1140148 | cell-based format | Scientific Literature | |
15. | ALA1028294 | F | Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein by GTPgammaS assay relative to histamine | Rattus norvegicus | 1 | ALA1140148 | cell-based format | Scientific Literature | |
16. | ALA960691 | B | Binding affinity to rat histamine H4 receptor | Rattus norvegicus | 2 | ALA1151749 | single protein format | Scientific Literature | |
17. | ALA960692 | F | Antagonist activity at rat histamine H4 receptor | Rattus norvegicus | 2 | ALA1151749 | assay format | Scientific Literature | |
18. | ALA1074193 | B | Binding affinity to rat histamine H4 receptor | Rattus norvegicus | 2 | ALA1157657 | single protein format | Scientific Literature | |
19. | ALA1116870 | F | Antagonist activity at rat histamine H4 receptor assessed as decrease in intracellular calcium by FLIPR | Rattus norvegicus | 38 | ALA1155405 | cell-based format | Scientific Literature | |
20. | ALA1116877 | B | Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation counting | Rattus norvegicus | 5 | ALA1155405 | single protein format | Scientific Literature |