# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1286072 | B | Inhibition of Mycobacterium tuberculosis zinc dependent class 2 Fba | Mycobacterium tuberculosis | 7 | ALA1275330 | single protein format | Scientific Literature | |
2. | ALA2354305 | F | PubChem BioAssay. Fluorescence-based biochemical high throughput dose response assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis. (Class of assay: confirmatory) | 174 | ALA1201862 | assay format | PubChem BioAssays | ||
3. | ALA3888734 | B | Enzymatic Assay: Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a product such as dihydroxyacetone phosphate (DHAP) or glyceraldehyde 3-phosphate (GAP). If the activity is measurably lower in the presence of the candidate compound than in its absence, then the compound has FBA inhibitory activity and is a candidate antibiotic and antiparasitic compound. The compound may also be screened with recombinant or isolated Class I FBA (for example, of human or mammalian origin) to determine cross-inhibition. | 4 | ALA3886809 | single protein format | BindingDB Database |