# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1043841 | B | Residual activity of VRK1 at 1 uM by microplate scintillation counting | 3 | single protein format | Scientific Literature | |||
2. | ALA1047761 | B | Residual activity of VRK1 at 0.1 uM by microplate scintillation counting | 3 | single protein format | Scientific Literature | |||
3. | ALA1073370 | B | Residual activity of VRK1 at 10 uM by microplate scintillation counting | 3 | single protein format | Scientific Literature | |||
4. | ALA1292151 | B | Inhibition of human VRK1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA2352133 | B | Inhibition of VRK1 (unknown origin) using [gamma-33P]ATP assessed as residual activity at 3 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA3134657 | B | Inhibition of VRK1 (unknown origin) using RBER-CHKtide as substrate after 60 mins by scintillation counting | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA3242864 | B | Inhibition of human VRK1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA3430845 | B | Delta TM value showing the stabilisation of VRK1 produced by compound binding | Homo sapiens | 156 | single protein format | Scientific Literature | ||
9. | ALA3631621 | B | Inhibition of VRK1 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
10. | ALA3749901 | B | Inhibition of human VRK1 using [KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK] as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA3816876 | B | Inhibition of human VRK1 at 1 uM using [KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK] as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA4178327 | B | Inhibition of recombinant human full length N-terminal GST-tagged VRK1 expressed in baculovirus infected Sf9 cells assessed as change in enzyme activity at 1 uM in presence of 2 uM ATP relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA4307650 | B | Binding affinity to recombinant full length N-terminal His-tagged VRK1 (unknown origin) (1 to 396 residues) expressed in Escherichia coli BL 21 DE3-R3 cells assessed as change in melting temperature at 10 uM by thermal shift assay using differential scanning fluorimetry | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
14. | ALA4307651 | B | Inhibition of full length wild-type VRK1 (unknown origin) expressed in insect cells using ULight-Histone 3-Thr3 peptide as substrate incubated for 30 mins followed by substrate addition further incubated for 75 mins by fluorescence based assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
15. | ALA4307653 | B | Binding affinity to recombinant full length N-terminal His-tagged VRK1 (unknown origin) (1 to 396 residues) expressed in Escherichia coli BL 21 DE3-R3 cells assessed as dissociation constant at by isothermal titration method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4314959 | B | Inhibition of human VRK1 assessed as residual activity at 10 uM by radiometric method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
17. | ALA4327922 | B | Inhibition of human VRK1 assessed as residual activity at 1 uM using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate by [gamma-33P]-ATP assay relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
18. | ALA4328286 | B | Inhibition of human VRK1 assessed as residual activity at 100 uM using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate by [gamma-33P]-ATP assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA4328650 | B | Inhibition of human VRK1 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate by [gamma-33P]-ATP assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
20. | ALA4335337 | B | Inhibition of human VRK1 assessed as residual activity at 1 uM by radiometric method relative to control | Homo sapiens | 2 | single protein format | Scientific Literature |