# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1291422 | B | Inhibition of Syrian hamster prion protein (109-149) aggregation assessed as changes in light scattering at 1 uM by spectrofluorimetric analysis relative to control | Mesocricetus auratus | 7 | single protein format | Scientific Literature | ||
2. | ALA1291423 | B | Inhibition of Syrian hamster prion protein (109-149) aggregation assessed as changes in light scattering at 0.2 uM by spectrofluorimetric analysis relative to control | Mesocricetus auratus | 2 | single protein format | Scientific Literature | ||
3. | ALA1291424 | B | Inhibition of Syrian hamster prion protein (109-149) aggregation assessed as changes in light scattering at 0.1 uM by spectrofluorimetric analysis relative to control | Mesocricetus auratus | 2 | single protein format | Scientific Literature | ||
4. | ALA1291425 | B | Inhibition of Syrian hamster prion protein (109-149) aggregation assessed as compound concentration required to inhibit 50% aggregation by spectrofluorimetric analysis | Mesocricetus auratus | 7 | single protein format | Scientific Literature | ||
5. | ALA1291749 | B | Reduction of thioflavin T binding to Syrian hamster prion protein (109-149) at 10 uM after 10 mins by fluorescence assay | Mesocricetus auratus | 5 | single protein format | Scientific Literature | ||
6. | ALA4179214 | B | Binding affinity to Syrian hamster PrPC | Mesocricetus auratus | 6 | single protein format | Scientific Literature | ||
7. | ALA4179215 | B | Binding affinity to C-terminal 6x-His-tagged Syrian hamster PrPC (90 to 232 residues) by 15N-HSQC NMR spectroscopy | Mesocricetus auratus | 1 | single protein format | Scientific Literature | ||
8. | ALA4179216 | B | Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blot | Mesocricetus auratus | 21 | single protein format | Scientific Literature | ||
9. | ALA4179217 | B | Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by measuring PrPSc level relative to untreated control | Mesocricetus auratus | 22 | single protein format | Scientific Literature |