| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2020290 | B | Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by reporter gene assay | Homo sapiens | 68 | cell-based format | Scientific Literature | ||
| 2. | ALA2020296 | B | Inhibition of NOD-1 in human MCF7 cells assessed as inhibition of gamma-tri-DAP-induced IL8 secretion at 0.25 to 5 uM by ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA2020299 | B | Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity at 0.25 to 25 uM by reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA1614306 | F | PUBCHEM_BIOASSAY: SAR analysis of NF-kB dependent luciferase using PMA/Ionomycin as an inducer. (Class of assay: confirmatory) [Related pubchem assays: 1578, 1575 (Summary AID.)] | Homo sapiens | 7 | assay format | PubChem BioAssays | ||
| 5. | ALA1614411 | F | PUBCHEM_BIOASSAY: SAR analysis of NF-kappaB dependent luciferase using Doxorubicin as an inducer - Set 2. (Class of assay: confirmatory) [Related pubchem assays: 1578, 1575 (Summary AID.)] | Homo sapiens | 16 | assay format | PubChem BioAssays | ||
| 6. | ALA1693669 | F | Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysis | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 7. | ALA1738025 | F | PUBCHEM_BIOASSAY: SAR analysis of compounds that inhibit NOD1 revised. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1575, AID1578, AID2335, AID2466, AID2469, AID2505, AID2798, AID2800] | Homo sapiens | 284 | assay format | PubChem BioAssays | ||
| 8. | ALA1614013 | F | PUBCHEM_BIOASSAY: SAR analysis of NF-kappaB dependent luciferase using PMA/Ionomycin as an inducer - 2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1575, AID1578] | Homo sapiens | 16 | assay format | PubChem BioAssays | ||
| 9. | ALA1614075 | F | PUBCHEM_BIOASSAY: SAR analysis of NF-kB dependent luciferase using DAP as an inducer. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1566, AID1575, AID1578, AID1579, AID1849, AID1852, AID2793] | Homo sapiens | 7 | assay format | PubChem BioAssays | ||
| 10. | ALA1613826 | F | PUBCHEM_BIOASSAY: SAR analysis of NF-kappaB dependent luciferase using DAP as an inducer - Set 2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1566, AID1575, AID1578, AID1579, AID1849, AID1852, AID2264] | Homo sapiens | 16 | assay format | PubChem BioAssays | ||
| 11. | ALA1738032 | F | PUBCHEM_BIOASSAY: SAR analysis of compounds that inhibit NOD1 - Set 2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1566, AID1575, AID1578, AID1849, AID1852, AID2333, AID2335, AID2798] | Homo sapiens | 20 | assay format | PubChem BioAssays | ||
| 12. | ALA1613901 | F | PUBCHEM_BIOASSAY: SAR analysis of NF-kB dependent luciferase using Doxorubicin as an inducer. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1575, AID1578] | Homo sapiens | 7 | assay format | PubChem BioAssays | ||
| 13. | ALA1738190 | F | PUBCHEM_BIOASSAY: SAR analysis of compounds that inhibit NOD1 - Set 3. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1566, AID1575, AID1578, AID1849, AID1852, AID2333, AID2335, AID2466] | Homo sapiens | 39 | assay format | PubChem BioAssays | ||
| 14. | ALA1769280 | B | Induction of human NOD1 activity expressed in HEK293T cells assessed as NFKB activation at 1 to 100 ng/ml by luciferase reporter assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA1769281 | B | Induction of human NOD1 activity expressed in HEK293T cells assessed as NFKB activation at 0.1 to 1000 ng/ml by luciferase reporter assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 16. | ALA1769282 | B | Induction of human NOD1 activity expressed in HEK293T cells assessed as NFKB activation at 5 mM | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA2437997 | B | Agonist activity at human Nod1 expressed in human Ramos cells assessed as reduction of NF-kappaB transcriptional activity at 10 uM after 24 hrs by SEAP reporter gene assay in presence of nod1 antagonist noditinib-1 | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 18. | ALA2437998 | B | Agonist activity at human Nod1 expressed in human Ramos-Blue cells assessed as increase in NF-kappaB transcriptional activity at 10 uM after 24 hrs by SEAP reporter gene assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 19. | ALA5254198 | B | Antagonist activity at NOD1 in human THP-1 cells assessed as decrease in C12-iE-DAP-induced IkappaBalpha protein expression level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5254477 | B | Antagonist activity at NOD1 in human THP-1 cells assessed as decrease in C12-iE-DAP-induced IkappaBalpha phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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