# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1225186 | B | Binding affinity to Nur77 receptor expressed in human BGC823 cells | 1 | cell-based format | Scientific Literature | |||
2. | ALA1225187 | F | Agonist activity at nuclear orphan receptor Nur77 in human BGC823 cells bearing beta-galactosidase expression vector assessed as transcriptional activation of NurRE reporter gene after 12 hrs by luciferase assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA1225188 | F | Agonist activity at nuclear orphan receptor Nur77 in human BGC823 cells bearing beta-galactosidase expression vector assessed as transcriptional activation of retinoic acid receptor response element after 12 hrs by luciferase assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA1225189 | F | Agonist activity at nuclear orphan receptor Nur77 in human BGC823 cells bearing beta-galactosidase expression vector assessed as transcriptional activation of estrogen receptor reporter gene after 12 hrs by luciferase assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA1225190 | F | Agonist activity at nuclear orphan receptor Nur77 in human BGC823 cells bearing beta-galactosidase expression vector assessed as transcriptional activation of thyroid receptor reporter gene after 12 hrs by luciferase assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA1225191 | B | Binding affinity to GST-tagged nuclear orphan receptor Nur77 at 25 degC by fluorescence quenching analysis | 2 | single protein format | Scientific Literature | |||
7. | ALA1227058 | B | Binding affinity to nuclear orphan receptor Nur77-ligand binding domain at 5 Um by fluorescence quenching analysis | 1 | single protein format | Scientific Literature | |||
8. | ALA1227059 | B | Binding affinity to nuclear orphan receptor Nur77-DNA binding domain at 5 uM by fluorescence quenching analysis | 1 | single protein format | Scientific Literature | |||
9. | ALA1227060 | B | Binding affinity to nuclear orphan receptor Nur77 Y453A mutant at 5 uM by fluorescence quenching analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
10. | ALA1227061 | B | Binding affinity to nuclear orphan receptor Nur77 assessed as conformational change in receptor by CD spectroscopic | 2 | single protein format | Scientific Literature | |||
11. | ALA1227062 | B | Binding affinity to nuclear orphan receptor Nur77 by sedimentation equilibrium assay | 1 | single protein format | Scientific Literature | |||
12. | ALA1227063 | F | Agonist activity at nuclear orphan receptor Nur77 expressed in human BGC823 cells co-transfected with fused GAL4-Nur77 assessed as transactivation after 12 hrs by luciferase reporter gene assay | 1 | cell-based format | Scientific Literature | |||
13. | ALA1227064 | F | Agonist activity at nuclear orphan receptor Nur77 expressed in human BGC823 cells co-transfected with fused GAL4-LBD assessed as transactivation after 12 hrs by luciferase reporter gene assay | 1 | cell-based format | Scientific Literature | |||
14. | ALA1227065 | F | Agonist activity at nuclear orphan receptor Nur77 expressed in human BGC823 cells co-transfected with fused GAL4-DBD assessed as transactivation after 12 hrs by luciferase reporter gene assay | 1 | cell-based format | Scientific Literature | |||
15. | ALA1227066 | F | Agonist activity at nuclear orphan receptor Nur77 expressed in human BGC823 cells co-transfected with fused GAL4-Y453A assessed as transactivation after 12 hrs by luciferase reporter gene assay | 1 | cell-based format | Scientific Literature | |||
16. | ALA1227264 | B | Binding affinity to NuR77-LBD receptor expressed in human BGC823 cells | 1 | cell-based format | Scientific Literature | |||
17. | ALA1227265 | B | Binding affinity to Nur77 Y453A mutant expressed in human BGC823 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA1227266 | F | Agonist activity at nuclear orphan receptor Nur77 expressed in human BGC823 cells co-transfected with pLuc-2900 containing Nr4a1 promoter assessed as transcriptional activity | 1 | cell-based format | Scientific Literature | |||
19. | ALA1227267 | F | Agonist activity at nuclear orphan receptor Nur77 expressed in human BGC823 cells co-transfected with pLuc-3500 containing Nr4a1 promoter assessed as transcriptional activity | 1 | cell-based format | Scientific Literature | |||
20. | ALA1227268 | F | Agonist activity at nuclear orphan receptor Nur77 expressed in human BGC823 cells co-transfected with pLuc-500 containing Nr4a1 promoter assessed as transcriptional activity | 1 | cell-based format | Scientific Literature |