| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1614197 | F | PUBCHEM_BIOASSAY: Concentration response confirmation assay for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) [Related pubchem assays: 2551 (Primary screen tested at 6 concentrations from 46 uM to 3 nM)] | Mus musculus | 217 | assay format | PubChem BioAssays | ||
| 2. | ALA1614007 | F | PUBCHEM_BIOASSAY: Concentration response confirmation VP16 counterscreen for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) [Related pubchem assays: 2546 (Primary counterscreen tested in the VP16 cell line at 6 concentrations from 46 uM to 3 nM)] | Mus musculus | 154 | assay format | PubChem BioAssays | ||
| 3. | ALA1614087 | F | PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) | Mus musculus | 51,950 | assay format | PubChem BioAssays | ||
| 4. | ALA1614441 | F | PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) | Mus musculus | 36,283 | assay format | PubChem BioAssays | ||
| 5. | ALA2327329 | B | Antagonist activity RORgammat in C57BL/6 mouse regulatory T cells assessed as inhibition of cell differentiation at 2 uM after 5 days by flow cytometry | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2327330 | B | Antagonist activity RORgammat in C57BL/6 mouse Th1 cells assessed as inhibition of cell differentiation at 2 uM after 5 days by flow cytometry | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2327331 | B | Antagonist activity RORgammat in C57BL/6 mouse CD4+ T cells assessed as inhibition of cell differentiation at 2 uM after 5 days by flow cytometry | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA2327332 | B | Antagonist activity RORgammat in C57BL/6 mouse Th17 cells assessed as inhibition of cell differentiation at 2 uM after 5 days by flow cytometry | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3106084 | B | Inhibition of RORgammat receptor ligand binding domain in mouse spleen CD4+ T cells assessed as inhibition of IL-17 production at 10 uM after 3 days by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3106085 | B | Inhibition of RORgammat receptor ligand binding domain in mouse spleen CD4+ T cells assessed as inhibition of IL-17 production after 3 days by ELISA | Mus musculus | 20 | cell-based format | Scientific Literature | ||
| 11. | ALA3110731 | B | Inverse agonist activity at RORgammat in mouse Th17 cells assessed as effect on cell differentiation measured as IL-17 level after 3 days by ELISA | Mus musculus | 10 | cell-based format | Scientific Literature | ||
| 12. | ALA3227574 | B | Inverse agonist activity at mouse ROR gamma expressed in CHO-K1 cells after 24 hrs by luciferase reporter gene assay relative to vehicle control response | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA3227578 | B | Inhibition of mouse Gal4 DNA binding domain-fused ROR gamma expressed in Drosophila S2 cells assessed as inhibition of transcriptional activity by luciferase reporter assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3369184 | B | Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 production | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA3370837 | B | Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 production at 10 uM | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 16. | ALA3599135 | B | Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISA | Mus musculus | 22 | cell-based format | Scientific Literature | ||
| 17. | ALA3607384 | B | Inverse agonist activity at RORgammat in mouse Th17 cells assessed as inhibition of IL-17 production after 3 days by ELISA | Mus musculus | 12 | cell-based format | Scientific Literature | ||
| 18. | ALA3776821 | B | Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase reporter gene assay | Mus musculus | 28 | cell-based format | Scientific Literature | ||
| 19. | ALA4007093 | B | Antagonist activity at mouse Gal4-fused DBD RORgamma LBD (Pro-261-end) expressed in TRex-CHOK1 cells after 20 hrs by luciferase reporter gene assay | Mus musculus | 15 | cell-based format | Scientific Literature | ||
| 20. | ALA4144983 | B | Inverse agonist activity at RORgammat in mouse CD positive T cells assessed as inhibition of Th17 cell differentiation by measuring 1L-17 release after 3 days by ELISA | Mus musculus | 2 | cell-based format | Scientific Literature |
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