| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1614117 | F | PUBCHEM_BIOASSAY: qHTS Confirmation Assay for Inhibitors of Bloom's syndrome helicase (BLM). (Class of assay: confirmatory) [Related pubchem assays: 2528 (qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM)), 593 (Fluorescein region spectral profiling screen), 2386 (Probe Development Summary for Inhibitors of Bloom's syndrome helicase (BLM)), 594 (Rhodamine region spectral profiling screen), 2364 (qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM))] | Homo sapiens | 167 | assay format | PubChem BioAssays | ||
| 2. | ALA1614522 | F | PUBCHEM_BIOASSAY: qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 594 (Rhodamine region spectral profiling screen)] | Homo sapiens | 777 | assay format | PubChem BioAssays | ||
| 3. | ALA1614067 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 2386 (Probe Development Summary for Inhibitors of Bloom's syndrome helicase (BLM)), 594 (Rhodamine region spectral profiling screen), 2364 (qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM))] | Homo sapiens | 2,514 | assay format | PubChem BioAssays | ||
| 4. | ALA2428102 | B | Inhibition of BLM in human PSNF5 cells assessed as increase of sister chromatid exchange at 1 to 5 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA2428103 | B | Displacement of TAMRA-labeled oligonucleotide from BLM (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA2428104 | B | Inhibition of BLM (unknown origin) binding to single-stranded DNA by fluorescence polarization analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA2428105 | B | Competitive inhibition of BLM (unknown origin) using ATP by Lineweaver-Burk double reciprocal plot analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA2428261 | B | Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay | Homo sapiens | 57 | single protein format | Scientific Literature | ||
| 9. | ALA3214809 | F | PubChem BioAssay. qHTS for Inhibitors of WRN Helicase: BLM Helicase Counterscreen for WRN Inhibitors. (Class of assay: confirmatory) | 505 | assay format | PubChem BioAssays | |||
| 10. | ALA3377969 | B | Inhibition of BLM helicase (unknown origin) binding to DNA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA3377970 | B | Inhibition of BLM helicase (unknown origin) assessed as branch migration activity | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4320939 | B | Inhibition of ATP hydrolysis activity of His-tagged BLM (unknown origin) expressed in Escherichia coli BL21 (DE3) at 1 to 10 uM | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4320941 | B | Inhibition of His-tagged BLM E1143A mutant (unknown origin) binding to DNA assessed as effect on unbound DNA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4320942 | B | Inhibition of His-tagged BLM I1168A mutant (unknown origin) binding to DNA assessed as effect on unbound DNA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4320943 | B | Inhibition of His-tagged BLM M1111A mutant (unknown origin) binding to DNA assessed as effect on unbound DNA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4320944 | B | Inhibition of His-tagged BLM H996A mutant (unknown origin) binding to DNA assessed as effect on unbound DNA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA4320945 | B | Inhibition of His-tagged BLM Y995A mutant (unknown origin) binding to DNA assessed as effect on unbound DNA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4320948 | B | Inhibition of BLM in human HCT116 cells assessed as induction of RAD51 recruitment to DSB sites on chromosomes at 0.5 to 1 uM after 48 hrs by ChIP assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4320949 | B | Inhibition of BLM in human HCT116 cells assessed as induction of HRR up-regulation at 1 uM after 24 hrs by GFP-based flow cytometry relative to untreated control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4320950 | B | Inhibition of His-tagged BLM (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in BLM helicase unwinding activity at 50 uM using 5'-biotin labeled forked-DNA as substrate after 1 hr by PAGE analysis | Homo sapiens | 5 | assay format | Scientific Literature |
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