| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA712894 | B | Inhibition of metallo-beta-lactamase (MBL) from Pseudomonas aeruginosa mediated by the plasmid-borne IMP-1 enzyme. | Pseudomonas aeruginosa | 25 | ALA1131986 | single protein format | Scientific Literature | |
| 2. | ALA1614346 | B | PubChem BioAssay. Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase. (Class of assay: confirmatory) | Pseudomonas aeruginosa | 93 | ALA1201862 | single protein format | PubChem BioAssays | |
| 3. | ALA1614353 | B | PubChem BioAssay. FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. (Class of assay: confirmatory) | Pseudomonas aeruginosa | 123 | ALA1201862 | single protein format | PubChem BioAssays | |
| 4. | ALA1613891 | B | PubChem BioAssay. Epi-absorbance-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. (Class of assay: confirmatory) | Pseudomonas aeruginosa | 123 | ALA1201862 | single protein format | PubChem BioAssays | |
| 5. | ALA1676791 | B | Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysis | Pseudomonas aeruginosa | 5 | ALA1671717 | single protein format | Scientific Literature | |
| 6. | ALA1676792 | B | Activity of Pseudomonas aeruginosa beta-lactamase IMP-1 by UV spectrophotometric analysis | Pseudomonas aeruginosa | 3 | ALA1671717 | single protein format | Scientific Literature | |
| 7. | ALA1676793 | B | Ratio of Kcat to Km for Pseudomonas aeruginosa beta-lactamase IMP-1 by UV spectrophotometric analysis | Pseudomonas aeruginosa | 3 | ALA1671717 | single protein format | Scientific Literature | |
| 8. | ALA1913282 | B | Inhibition of Pseudomonas aeruginosa metallo-beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) using CENTA as substrate at 10 uM by spectrophotometric analysis | Pseudomonas aeruginosa | 11 | ALA1909495 | assay format | Scientific Literature | |
| 9. | ALA1913283 | B | Competitive inhibition of Pseudomonas aeruginosa metallo-beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) using CENTA as substrate by spectrophotometric analysis | Pseudomonas aeruginosa | 6 | ALA1909495 | assay format | Scientific Literature | |
| 10. | ALA1913422 | B | Uncompetitive inhibition of Pseudomonas aeruginosa metallo-beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) using CENTA as substrate by spectrophotometric analysis | Pseudomonas aeruginosa | 4 | ALA1909495 | assay format | Scientific Literature | |
| 11. | ALA1936965 | B | Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) at 1000 uM using CENTA as chromogenic substrate | Pseudomonas aeruginosa | 15 | ALA1932941 | assay format | Scientific Literature | |
| 12. | ALA1936966 | B | Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) at 100 uM using CENTA as chromogenic substrate | Pseudomonas aeruginosa | 15 | ALA1932941 | assay format | Scientific Literature | |
| 13. | ALA1936967 | B | Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) at 10 uM using CENTA as chromogenic substrate | Pseudomonas aeruginosa | 25 | ALA1932941 | assay format | Scientific Literature | |
| 14. | ALA1936968 | B | Competitive inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as formation of 4-nitrothiophenolate at pH 7 using CENTA as chromogenic substrate | Pseudomonas aeruginosa | 8 | ALA1932941 | single protein format | Scientific Literature | |
| 15. | ALA1936969 | B | Uncompetitive inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as formation of 4-nitrothiophenolate at pH 7 using CENTA as chromogenic substrate | Pseudomonas aeruginosa | 9 | ALA1932941 | single protein format | Scientific Literature | |
| 16. | ALA2090106 | B | Inhibition of recombinant Pseudomonas aeruginosa MBL IMP-1 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis | Pseudomonas aeruginosa | 18 | ALA2086282 | single protein format | Scientific Literature | |
| 17. | ALA2090108 | B | Inhibition of recombinant Pseudomonas aeruginosa MBL IMP-1 using nitrocefin as substrate after 12 hrs by UV-spectrophotometric analysis | Pseudomonas aeruginosa | 1 | ALA2086282 | single protein format | Scientific Literature | |
| 18. | ALA2114904 | F | PubChem BioAssay. Late stage results from the probe development effort to identify common IMP-1 and VIM-2 inhibitors: Epi-absorbance-based biochemical dose response assay for inhibitors of IMP-1metallo-beta-lactamase. (Class of assay: confirmatory) | Pseudomonas aeruginosa | 6 | ALA1201862 | assay format | PubChem BioAssays | |
| 19. | ALA3076630 | B | Inhibition of Pseudomonas aeruginosa IMP1 metallo-beta-lactamase | Pseudomonas aeruginosa | 49 | ALA3044597 | single protein format | Scientific Literature | |
| 20. | ALA4139265 | B | Inhibition of beta-lactamase in Pseudomonas aeruginosa ATCC 27853 assessed as potentiation of amoxicillin induced antibacterial activity at 10 to 100% amoxicillin to compound dilution after 24 hrs by agar well diffusion method | Pseudomonas aeruginosa | 2 | ALA4138092 | single protein format | Scientific Literature |
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