# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1794584 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] | 63,980 | assay format | PubChem BioAssays | |||
2. | ALA1614270 | F | PUBCHEM_BIOASSAY: SMAD Transcription Factor Inhibitors Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 630 (Primary screen preceding this dose response confirmation assay.)] | Homo sapiens | 30 | assay format | PubChem BioAssays | ||
3. | ALA1614060 | F | PUBCHEM_BIOASSAY: SMAD Transcription Factor Inhibitors Secondary Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 715 (Primary dose response assay preceding this secondary confirmation assay.), 630 (Primary screen preceding this secondary confirmation assay.)] | Homo sapiens | 35 | assay format | PubChem BioAssays | ||
4. | ALA2401266 | B | Inhibition of TGF-beta-induced Smad3 phosphorylation in human MDA-MB-231 cells treated 12 hrs before TGF-beta challenge measured after 1 hr by Western blotting | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA3214991 | F | PubChem BioAssay. qHTS for Inhibitors of TGF-b: CCL64 Cells Orthogonal Assay for Cherry Picks. (Class of assay: confirmatory) | 1,262 | assay format | PubChem BioAssays | |||
6. | ALA3215184 | F | PubChem BioAssay. qHTS for Inhibitors of TGF-b: Confirmation of Cherry Picks. (Class of assay: confirmatory) | 1,447 | assay format | PubChem BioAssays | |||
7. | ALA3215277 | F | PubChem BioAssay. qHTS for Inhibitors of TGF-b: Hit Validation in HepG2 Cells using COP promoter. (Class of assay: confirmatory) | 738 | cell-based format | PubChem BioAssays | |||
8. | ALA4669333 | B | Inhibition of TGF-beta induced SMAD3 phosphorylation in human A549 cells at 5 to 10 uM pretreated with compound for 2 hrs followed by TGF-beta stimulation by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA4669337 | B | Inhibition of SMAD3 (unknown origin) phosphorylation transfected in NIH3T3-pCAGA12-Luc cells cotransfected with firefly luciferase by CAGA-based luciferase reporter assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA4669338 | B | Inhibition of SMAD3 (unknown origin) phosphorylation transfected in NIH3T3-pCAGA12-Luc cells cotransfected with firefly luciferase at 10 uM by CAGA-based luciferase reporter assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
11. | ALA4669339 | B | Inhibition of SMAD3 (unknown origin) phosphorylation transfected in NIH3T3-pCAGA12-Luc cells cotransfected with firefly luciferase at 5 uM by CAGA-based luciferase reporter assay relative to control | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
12. | ALA4841541 | B | Inhibition of TGF-beta1 induced SMAD3 phosphorylation in human LX2 cells by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |