# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1614315 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488939] | Homo sapiens | 4,782 | ALA1201862 | assay format | PubChem BioAssays | |
2. | ALA1794428 | F | PUBCHEM_BIOASSAY: Inhibitors of Eya2ED: Hit Confirmation in Primary Screen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488837, AID488939] | 43 | ALA1201862 | assay format | PubChem BioAssays | ||
3. | ALA3214863 | F | PubChem BioAssay. qHTS for Inhibitors of the Phosphatase Activity of Eya2: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) | 960 | ALA1201862 | assay format | PubChem BioAssays | ||
4. | ALA4257241 | B | Inhibition of human Eya2 catalytic domain by p-nitrophenylphosphate assay | Homo sapiens | 1 | ALA4257222 | single protein format | Patent Bioactivity Data | |
5. | ALA4257245 | B | Inhibition of human Eya2 catalytic domain using KKATOASQEpY phospho-peptide substrate | Homo sapiens | 1 | ALA4257222 | single protein format | Patent Bioactivity Data | |
6. | ALA4257253 | B | Inhibition of Eya2 (unknown origin) expressed in human MCF10A cells assessed as reduction in cell migration | Homo sapiens | 3 | ALA4257222 | cell-based format | Patent Bioactivity Data | |
7. | ALA4257254 | B | Inhibition of Eya2 (unknown origin) expressed in human MCF10A cells assessed as reduction in cell migration at 1 uM | Homo sapiens | 1 | ALA4257222 | cell-based format | Patent Bioactivity Data | |
8. | ALA4257255 | B | Inhibition of Eya2 D250N mutant (unknown origin) expressed in human MCF10A cells assessed as reduction in cell migration | Homo sapiens | 3 | ALA4257222 | cell-based format | Patent Bioactivity Data | |
9. | ALA4422502 | B | Inhibition of human Eya2 catalytic domain using para-nitrophenol phosphate substrate incubated for 30 mins | Homo sapiens | 1 | ALA4421732 | single protein format | Patent Bioactivity Data | |
10. | ALA4422505 | B | Inhibition of human Eya2 catalytic domain using phospho-peptide KKATQASQEpY substrate | Homo sapiens | 1 | ALA4421732 | single protein format | Patent Bioactivity Data | |
11. | ALA4422513 | B | Inhibition of EYA2 (unknown origin) stably transfected in human MCF10A cells assessed as inhibition of cell migration at 7.5 uM by transwell assay | Homo sapiens | 3 | ALA4421732 | cell-based format | Patent Bioactivity Data | |
12. | ALA4422514 | B | Inhibition of EYA2 (unknown origin) stably transfected in human MCF10A cells assessed as inhibition of cell migration by transwell assay | Homo sapiens | 3 | ALA4421732 | cell-based format | Patent Bioactivity Data | |
13. | ALA4422515 | B | Inhibition of EYA2 D250N mutant (unknown origin) stably transfected in human MCF10A cells assessed as inhibition of cell migration at 7.5 uM by transwell assay relative to control | Homo sapiens | 3 | ALA4421732 | cell-based format | Patent Bioactivity Data | |
14. | ALA4422540 | B | Inhibition of EYA2 (unknown origin) stably transfected in human MCF10A cells assessed as inhibition of cell migration at 1 uM by transwell assay relative to control | Homo sapiens | 1 | ALA4421732 | cell-based format | Patent Bioactivity Data | |
15. | ALA4422541 | B | Inhibition of GST-fused human Eya2 ED (253 to 538 residues) expressed in Escherichia coli pre-incubated for 10 mins followed by OMFP substrate addition and further incubated for 30 mins by fluorescence based assay relative to control | Homo sapiens | 3 | ALA4421733 | assay format | Patent Bioactivity Data | |
16. | ALA4422542 | B | Inhibition of GST-fused human Eya2 ED (253 to 538 residues) expressed in Escherichia coli pre-incubated for 10 mins followed by OMFP substrate addition and further incubated for 30 mins by fluorescence based assay | Homo sapiens | 20 | ALA4421733 | assay format | Patent Bioactivity Data | |
17. | ALA4422543 | B | Inhibition of GST-fused human Eya2 ED (253 to 538 residues) expressed in Escherichia coli at 0.1 to 100 mM pre-incubated for 10 mins followed by OMFP substrate addition and further incubated for 30 mins by fluorescence based assay | Homo sapiens | 5 | ALA4421733 | assay format | Patent Bioactivity Data | |
18. | ALA4422544 | B | Inhibition of GST-fused human Eya2 ED (253 to 538 residues) expressed in Escherichia coli assessed as reduction in phosphatase activity using OMFP as substrate in presence of 1 mM MgCl2 by FITS assay | Homo sapiens | 1 | ALA4421733 | assay format | Patent Bioactivity Data | |
19. | ALA4422545 | B | Inhibition of GST-fused human Eya2 ED (253 to 538 residues) expressed in Escherichia coli assessed as reduction in phosphatase activity using OMFP as substrate in presence of 5 uM MgCl2 by FITS assay | Homo sapiens | 1 | ALA4421733 | assay format | Patent Bioactivity Data | |
20. | ALA4422546 | B | Inhibition of GST-fused human Eya2 ED (253 to 538 residues) expressed in Escherichia coli assessed as reduction in phosphatase activity using OMFP as substrate in absence of MgCl2 by FITS assay | Homo sapiens | 1 | ALA4421733 | assay format | Patent Bioactivity Data |