| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2049461 | B | Inhibition of N-terminus FLAG-tagged MEK5 expressed in baculovirus expression system using [gamma-33P]-ATP measured after 30 mins by scintillation counting | 1 | assay format | Scientific Literature | |||
| 2. | ALA2025865 | B | Inhibition of MAP2K5 at 1 uM relative to control | 1 | single protein format | Scientific Literature | |||
| 3. | ALA1908418 | B | Binding constant for MEK5 kinase domain | 72 | single protein format | Scientific Literature | |||
| 4. | ALA1924834 | B | Inhibition of N-terminus flag-tagged MEK5 expressed in baculovirus infected insect cells using [gamma33P]ATP as substrate after 60 mins by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 5. | ALA1941380 | B | Inhibition of MEK5 at 1 uM | 2 | single protein format | Scientific Literature | |||
| 6. | ALA2014950 | B | Inhibition of MAP2K5 at 10 uM | 1 | single protein format | Scientific Literature | |||
| 7. | ALA2150266 | B | Inhibition of N-terminal FLAG-tagged MEK5 expressed in baculovirus after 5 mins by scintillation counter | 1 | assay format | Scientific Literature | |||
| 8. | ALA1061190 | F | Concentration-dependent inhibition of ERK5 phosphorylation shift in EGF-stimulated HeLa cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA1114904 | B | Inhibition of MAP2K5 at 5 uM | 1 | single protein format | Scientific Literature | |||
| 10. | ALA1120768 | B | Inhibition of EGF-induced MEK5-mediated ERK1/2 phosphorylation in human HEK293 cells at 10 uM treated after 30 mins EGF challenge measured after 30 mins by Western blot analysis relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 11. | ALA1120769 | B | Inhibition of EGF-induced MEK5-mediated ERK5 phosphorylation in human HEK293 cells at 10 uM treated after 30 mins EGF challenge measured after 30 mins by Western blot analysis relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 12. | ALA1174908 | B | Inhibition of MEK5 at 10 uM | 2 | single protein format | Scientific Literature | |||
| 13. | ALA1244373 | B | Inhibition of MAP2K5 | 1 | single protein format | Scientific Literature | |||
| 14. | ALA1286034 | B | Activation of EGF-induced MEK5 activity in HEK293 cells assessed as phosphorylated ERK5 level at 10 uM after 1 hr by Western blotting relative to control | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 15. | ALA1286035 | B | Inhibition of EGF-induced MEK5 activity in HEK293 cells assessed as phosphorylated ERK5 level at 10 uM after 1 hr by Western blotting relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 16. | ALA1772050 | B | Binding affinity to human Mek5 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA2211522 | B | Inhibition of MAP2K5 | 1 | single protein format | Scientific Literature | |||
| 18. | ALA2210617 | B | Inhibition of MEK5 assessed as residual activity at 10 uM relative to control | 1 | single protein format | Scientific Literature | |||
| 19. | ALA2351309 | B | Inhibition of N-terminal FLAG-tagged MEK5 (unknown origin) expressed in baculovirus expression system incubated for 5 mins prior to [gamma-33P]ATP addition measured after 30 mins by scintillation counting analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA3088489 | B | Binding affinity to MEK5 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature |
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