| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1832991 | B | Binding affinity to second bromodomain of BRD2 assessed as change in melting temperature at 100 uM by differential scanning fluorimetry | 9 | single protein format | Scientific Literature | |||
| 2. | ALA1832992 | B | Binding affinity to first bromodomain of BRD2 assessed as change in melting temperature at 100 uM by differential scanning fluorimetry | 9 | single protein format | Scientific Literature | |||
| 3. | ALA1832995 | B | Displacement of H4Ac4 peptide from first bromodomain of human BRD2 by peptide displacement assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 4. | ALA1833000 | B | Inhibition of first bromodomain of BRD2 | 1 | single protein format | Scientific Literature | |||
| 5. | ALA1953100 | B | Binding affinity to His-6 tagged BRD2 expressed in Escherichia coli at 100 uM after 60 mins by fluorescence anisotropic analysis | 4 | assay format | Scientific Literature | |||
| 6. | ALA1953103 | B | Inhibition of His-6 tagged BRD2-RD12 precoupled with biotinylated tetra-acetylated histone H4 expressed in Escherichia coli assessed as protein-protein interaction at 50 uM after 1 hr by TR-FRET assay | 4 | assay format | Scientific Literature | |||
| 7. | ALA1953106 | B | Inhibition of His-6 tagged BRD2 expressed in Escherichia coli after 60 mins by fluorescence anisotropic analysis | 2 | assay format | Scientific Literature | |||
| 8. | ALA1953109 | B | Inhibition of His-6 tagged BRD2-RD12 interaction precoupled with biotinylated tetra-acetylated histone H4 expressed in Escherichia coli after 1 hr by TR-FRET assay | 1 | assay format | Scientific Literature | |||
| 9. | ALA1953113 | B | Binding affinity to His-6 tagged BRD2 expressed in Escherichia coli at 10 mM after 60 mins by fluorescence anisotropic analysis | 1 | assay format | Scientific Literature | |||
| 10. | ALA1958928 | B | Binding affinity to BRD2-BD1 assessed as change in melting temperature at 100 uM by protein stability shift assay | 12 | single protein format | Scientific Literature | |||
| 11. | ALA1958937 | B | Binding affinity to BRD2-BD1 assessed as change in melting temperature at 10 uM by protein stability shift assay | 6 | single protein format | Scientific Literature | |||
| 12. | ALA1959066 | B | Binding affinity to BRD2-BD2 assessed as change in melting temperature at 100 uM by protein stability shift assay | 12 | single protein format | Scientific Literature | |||
| 13. | ALA1959069 | B | Binding affinity to BRD2-BD2 assessed as change in melting temperature at 10 uM by protein stability shift assay | 6 | single protein format | Scientific Literature | |||
| 14. | ALA1960807 | B | Binding affinity to BRD2-BD1 by isothermal titration calorimetry | 1 | single protein format | Scientific Literature | |||
| 15. | ALA1958564 | B | Binding affinity to BRD2-BD1,2 by isothermal titration calorimetry | 2 | single protein format | Scientific Literature | |||
| 16. | ALA1958567 | B | Binding affinity to BRD2-BD1 by SPR spectroscopy | 1 | single protein format | Scientific Literature | |||
| 17. | ALA1958571 | B | Displacement of acetylated histone peptide from BRD2-BD1,2 by FRET assay | 2 | single protein format | Scientific Literature | |||
| 18. | ALA2433593 | B | Binding affinity to His6-tagged BRD2 (unknown origin) after 60 mins by fluorescence anisotropy binding Assay | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 19. | ALA2439862 | B | Inhibition of first bromodomain of BRD2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA2156110 | B | Binding affinity to N-terminal portion of human Brd2 containing bromodomain BD12 expressed in Escherichia coli by isothermal titration calorimetric analysis | Homo sapiens | 1 | assay format | Scientific Literature |
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