| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1738409 | Functional | PUBCHEM_BIOASSAY: Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1861, AID1880, AID1952, AID2148, AID2251, AID2257, AID485339] | Homo sapiens | 87 | ALA1201862 | cell-based format | PubChem BioAssays | |
| 2. | ALA1942829 | Binding | Displacement of [125]-hNPW23 from human NPBWR1 expressed in CHO-K1 cells membrane by scintillation proximity assay | Homo sapiens | 12 | ALA1938351 | cell-based format | Scientific Literature | |
| 3. | ALA1942830 | Functional | Antagonist activity at human NPBWR1 expressed in CHO-K1 cells assessed as inhibition of hNPW23 and forskolin-stimulated cAMP production after 1 hr by TR-FRET assay | Homo sapiens | 12 | ALA1938351 | cell-based format | Scientific Literature | |
| 4. | ALA1738387 | Functional | PUBCHEM_BIOASSAY: Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7): Intracellular calcium release. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1861, AID1880, AID1952, AID2148, AID2251, AID2257, AID463250, AID463251, AID463253] | Homo sapiens | 1 | ALA1201862 | cell-based format | PubChem BioAssays | |
| 5. | ALA1613980 | Functional | PUBCHEM_BIOASSAY: Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). (Class of assay: confirmatory) [Related pubchem assays: 1952 (Screening assay (GPR7 antagonists).), 1880 (Summary AID.)] | Homo sapiens | 126 | ALA1201862 | cell-based format | PubChem BioAssays | |
| 6. | ALA1963982 | Functional | PUBCHEM_BIOASSAY: Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7) Set 6. (Class of assay: confirmatory) | 83 | ALA1201862 | cell-based format | PubChem BioAssays | ||
| 7. | ALA1963862 | Functional | PUBCHEM_BIOASSAY: Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7) Set 5. (Class of assay: confirmatory) | 88 | ALA1201862 | cell-based format | PubChem BioAssays | ||
| 8. | ALA2213859 | Functional | Antagonist activity at human NPBWR1 expressed in HEK293T cells co-expressing Galphaqi3 assessed as calcium release after 15 mins by FLIPR assay assay | Homo sapiens | 66 | ALA2202992 | cell-based format | Scientific Literature | |
| 9. | ALA2319036 | Binding | Antagonist activity against human NPBWR1 expressed in HEK293 cells co-expressing Gqi3 assessed as inhibition of agonist-induced response by FLIPR assay | Homo sapiens | 73 | ALA2311420 | cell-based format | Scientific Literature | |
| 10. | ALA4701818 | Functional | Antagonist activity at human NPBWR1 assessed as inhibition of agonist-induced cAMP accumulation by cAMP assay | Homo sapiens | 45 | ALA4699486 | assay format | Scientific Literature | |
| 11. | ALA4701819 | Functional | Antagonist activity at recombinant human GPR7 assessed as reduction in agonist-induced inhibition of forskolin induced cAMP accumulation by measuring saturable parallel rightward shifts in agonist dose response by Schild plot analysis | Homo sapiens | 1 | ALA4699486 | assay format | Scientific Literature | |
| 12. | ALA4701820 | Binding | Competitive orthosteric antagonist activity at human GPR7 expressed in CHO cell membranes assessed as increase in Koff rate kinetics of [125I]-labeled human NPW23 at 0 to 30 uM by real-time scintillation proximity binding assay | Homo sapiens | 1 | ALA4699486 | cell membrane format | Scientific Literature | |
| 13. | ALA4701821 | Functional | Agonist activity at recombinant human GPR7 assessed as inhibition of forskolin induced cAMP accumulation | Homo sapiens | 1 | ALA4699486 | assay format | Scientific Literature | |
| 14. | ALA4883544 | Binding | PRESTO-Tango GPCRome screening (NPBW1) | 1 | ALA4507309 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 15. | ALA5127362 | Binding | Negative allosteric modulation activity at NPBWR1 (unknown origin) | Homo sapiens | 2 | ALA5126516 | single protein format | Scientific Literature | |
| 16. | ALA5158256 | Functional | Agonist activity at human NPBWR1 expressed in CHO-RD-HGA16 cells measured by calcium mobilization assay | Homo sapiens | 48 | ALA5154716 | cell-based format | Scientific Literature | |
| 17. | ALA5158257 | Functional | Agonist activity at human NPBWR1 expressed in CHO-RD-HGA16 cells measured by calcium mobilization assay relative to control | Homo sapiens | 28 | ALA5154716 | cell-based format | Scientific Literature | |
| 18. | ALA5158258 | Functional | Antagonist activity at human NPBWR1 expressed in CHO-RD-HGA16 cells at 10 uM measured by calcium mobilization assay relative to control | Homo sapiens | 15 | ALA5154716 | cell-based format | Scientific Literature | |
| 19. | ALA5158259 | Functional | Antagonist activity at human NPBWR1 expressed in CHO-RD-HGA16 cells measured by calcium mobilization assay | Homo sapiens | 7 | ALA5154716 | cell-based format | Scientific Literature | |
| 20. | ALA5158260 | Functional | Agonist activity at human NPBWR1 expressed in CHO cells measured by LANCE Ultra cAMP kit-based TR-FRET assay | Homo sapiens | 4 | ALA5154716 | cell-based format | Scientific Literature |
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