# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1048364 | B | Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assay | 49 | ALA1154105 | tissue-based format | Scientific Literature | ||
2. | ALA1244641 | B | Binding affinity to prostate specific antigen | 1 | ALA1240344 | tissue-based format | Scientific Literature | ||
3. | ALA2016158 | B | Inhibition of human kallikrein 3 | Homo sapiens | 1 | ALA2010718 | single protein format | Scientific Literature | |
4. | ALA2172814 | B | Inhibition of KLK3 | 2 | ALA2169752 | single protein format | Scientific Literature | ||
5. | ALA2172815 | B | Inhibition of human KLK3 using Mu-SRKSQQY-AMC as substrate by fluorometric analysis | Homo sapiens | 1 | ALA2169752 | single protein format | Scientific Literature | |
6. | ALA2383461 | B | Inhibition of PSA (unknown origin) using Mu-SRKSQQY-AMC as substrate by fluorescence assay | Homo sapiens | 1 | ALA2380267 | single protein format | Scientific Literature | |
7. | ALA2383462 | B | Inhibition of PSA (unknown origin) | Homo sapiens | 1 | ALA2380267 | single protein format | Scientific Literature | |
8. | ALA2383468 | B | Ratio of Ki for PSA (unknown origin) in RPMI in presence of 1% fetal bovine serum, 1% penicillin/streptomycin, 1% L-glutamine to Ki for PSA (unknown origin) in RPMI in absence of fetal bovine serum | Homo sapiens | 1 | ALA2380267 | single protein format | Scientific Literature | |
9. | ALA2383469 | B | Inhibition of PSA (unknown origin) in female plasma | Homo sapiens | 1 | ALA2380267 | single protein format | Scientific Literature | |
10. | ALA2383470 | B | Inhibition of PSA (unknown origin) in RPMI in presence of 1% fetal bovine serum, 1% penicillin/streptomycin, 1% L-glutamine | Homo sapiens | 1 | ALA2380267 | single protein format | Scientific Literature | |
11. | ALA2383471 | B | Inhibition of PSA (unknown origin) in RPMI in presence of 1% fetal bovine serum | Homo sapiens | 1 | ALA2380267 | single protein format | Scientific Literature | |
12. | ALA2383472 | B | Inhibition of PSA (unknown origin) in RPMI | Homo sapiens | 1 | ALA2380267 | single protein format | Scientific Literature | |
13. | ALA2383473 | B | Inhibition of PSA (unknown origin) in 50 mM TRIS.HCL and 100 mM NaCl buffer at pH 7.8 | Homo sapiens | 1 | ALA2380267 | single protein format | Scientific Literature | |
14. | ALA2383476 | B | Inhibition of PSA (unknown origin) binding to antichymotrypsin after overnight incubation by Western blot analysis | Homo sapiens | 1 | ALA2380267 | single protein format | Scientific Literature | |
15. | ALA2383477 | B | Inhibition of PSA (unknown origin) binding to alpha2-macroglobulin after overnight incubation by Western blot analysis | Homo sapiens | 1 | ALA2380267 | single protein format | Scientific Literature | |
16. | ALA2383481 | B | Inhibition of human seminal fluid PSA using Mu-SRKSQQY-AMC as substrate measured for 30 mins by fluorescence assay | Homo sapiens | 13 | ALA2380267 | single protein format | Scientific Literature | |
17. | ALA3097438 | A | Drug metabolism assessed as PSA (unknown origin)-mediated digestion assessed as compound remaining after 50 hrs by HPLC analysis | Homo sapiens | 1 | ALA3091437 | single protein format | Scientific Literature | |
18. | ALA3097439 | A | Prodrug activation assessed as PSA (unknown origin)-mediated digestion assessed as glutaryl-Hyp-Ala-Ser-Chg-Gln-OH level by LC-MS analysis | Homo sapiens | 1 | ALA3091437 | single protein format | Scientific Literature | |
19. | ALA3097440 | A | Drug metabolism assessed as PSA (unknown origin)-mediated digestion assessed as compound remaining after 4 hrs by HPLC analysis | Homo sapiens | 1 | ALA3091437 | single protein format | Scientific Literature | |
20. | ALA3097441 | A | Prodrug activation assessed as PSA (unknown origin)-mediated digestion assessed as half life at 1/100 enzyme-compound molar ratio by HPLC analysis | Homo sapiens | 4 | ALA3091437 | single protein format | Scientific Literature |