| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1614410 | F | PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] | Homo sapiens | 17,175 | ALA1201862 | assay format | PubChem BioAssays | |
| 2. | ALA2209114 | B | Inhibition of MLL1 using core histone as substrate preincubated for 10 mins followed by addition of [3H]SAM and incubated for 60 mins | 1 | ALA2202955 | single protein format | Scientific Literature | ||
| 3. | ALA2330197 | B | Inhibition of MLL1:WDR5:RbBP5:ASH2L complex (unknown origin) using histone H3 (1 to 25) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenosylmethionine | Homo sapiens | 1 | ALA2321656 | single protein format | Scientific Literature | |
| 4. | ALA2350644 | B | Inhibition of MLL1 (unknown origin) using [3H]SAM assessed as inhibition of biotinylated-H3 (21 to 44 amino acid residues) methylation at 0.1 to 100 uM after 1 hr by scintillation proximity assay | Homo sapiens | 1 | ALA2346640 | single protein format | Scientific Literature | |
| 5. | ALA3389598 | B | Inhibition of MLL1 (unknown origin) incubated for 15 mins before addition of biotinylated peptide H3 (1 to 21) and SAM by methylation assay | Homo sapiens | 1 | ALA3351464 | single protein format | Scientific Literature | |
| 6. | ALA3378781 | B | Inhibition of MLL1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by radioactive assay | Homo sapiens | 1 | ALA3351294 | single protein format | Scientific Literature | |
| 7. | ALA3399062 | B | Inhibition of MLL (unknown origin) by HMT assay | Homo sapiens | 2 | ALA3396964 | single protein format | Scientific Literature | |
| 8. | ALA3399149 | B | Ratio of S-adenosyl-L-homocysteine IC50 to compound IC50 for MLL (unknown origin) by HMT assay | Homo sapiens | 1 | ALA3396964 | single protein format | Scientific Literature | |
| 9. | ALA3583522 | B | Binding affinity to biotinylated MLL1 (1566 to 1784 amino acid residues) (unknown origin) expressed in Rosetta2 cells by bio-layer interferometry method | Homo sapiens | 1 | ALA3580597 | cell-based format | Scientific Literature | |
| 10. | ALA3592400 | B | Inhibition of MLL1 trimeric complex (unknown origin) assessed as incorporation of tritium labeled methyl group from [3H]-SAM to substrate at 1 uM after 1 hr by scintillation proximity assay relative to control | Homo sapiens | 1 | ALA3588844 | single protein format | Scientific Literature | |
| 11. | ALA3784087 | B | Inhibition of human MLL1 at 10 and 50 uM | Homo sapiens | 1 | ALA3779843 | single protein format | Scientific Literature | |
| 12. | ALA3801644 | B | Inhibition of SUMO-His-tagged MLL1 activity (unknown origin) expressed in Escherichia coli BL21(DE3) pLysS cells using histone H3 as substrate by scintillation counting method in presence of [3H]SAM | Homo sapiens | 1 | ALA3797181 | cell-based format | Scientific Literature | |
| 13. | ALA3821568 | B | Inhibition of MLL1 (unknown origin) at 1 to 50 uM by scintillation proximity assay | Homo sapiens | 1 | ALA3817823 | single protein format | Scientific Literature | |
| 14. | ALA3859060 | B | Inhibition of MLL1 (unknown origin) at 50 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by scintillation proximity assay | Homo sapiens | 1 | ALA3856251 | single protein format | Scientific Literature | |
| 15. | ALA4005616 | B | Inhibition of MLL1 (unknown origin) at 10 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by scintillation proximity assay | Homo sapiens | 1 | ALA4004823 | single protein format | Scientific Literature | |
| 16. | ALA4005645 | B | Inhibition of MLL1 (unknown origin) at 1 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by scintillation proximity assay | Homo sapiens | 1 | ALA4004823 | single protein format | Scientific Literature | |
| 17. | ALA4026524 | B | Inhibition of MLL1 (unknown origin) at 50 uM incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa method | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 18. | ALA4026525 | B | Inhibition of MLL1 (unknown origin) at 100 uM incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa method | Homo sapiens | 1 | ALA4024748 | single protein format | Scientific Literature | |
| 19. | ALA4051570 | B | Inhibition of MLL (unknown origin) assessed as change in melting temperature at 10 uM by SYPRO Orange-dye based fluorescence thermal shift assay | Homo sapiens | 1 | ALA4049437 | single protein format | Scientific Literature | |
| 20. | ALA4138819 | B | Binding affinity to 15N-labeled GST-tagged MLL1 PHD3 finger domain (1565 to 1627 residues) (unknown origin) expressed in Escherichia coli Rosetta2 BL21(DE3) pLysS cells by NMR Spectroscopy method | Homo sapiens | 1 | ALA4138076 | cell-based format | Scientific Literature |
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