| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1613762 | B | PUBCHEM_BIOASSAY: uHTS fluorescence assay for the identification of Human Immunodeficiency Virus Fusion Inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1991, AID434967] | Human immunodeficiency virus 1 | 368 | single protein format | PubChem BioAssays | ||
| 2. | ALA4136417 | B | Induction of conformational changes in HIV1 NLDH120 envelope glycoprotein gp120 transfected in COS cells assessed as increase in gp120 binding of monoclonal antibody 17b at 10 uM after 48 hrs by FACS | Human immunodeficiency virus 1 | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4137333 | B | Inhibition of [3H]BMS-488043 binding to HIV-1 JRFL gp120 after 1 hr by scintillation counting method | Human immunodeficiency virus 1 | 2 | single protein format | Scientific Literature | ||
| 4. | ALA4137350 | B | Binding affinity to HIV-1 JRFL gp120 assessed as half life for dissociation | Human immunodeficiency virus 1 | 2 | single protein format | Scientific Literature | ||
| 5. | ALA4182248 | B | Inhibition of HIV gp41 6-helix bundle formation preincubated with C34 and N36 for 30 mins | Human immunodeficiency virus | 3 | single protein format | Scientific Literature | ||
| 6. | ALA4182249 | B | Inhibition of HIV1 3B gp41-induced cell-cell fusion between viral protein expressing human H9 cells and MT-2 target cells assessed as number of syncytia formation treated for 2 hrs measured after 6 hrs | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4201482 | B | Inhibition of HIV1 envelope glycoprotein-mediated cell-cell fusion between HL2/3 cells stably expressing HIV Gag, Env, Tat, Rev and Nef proteins and human TZM-bl cells stably expressing high CD4 and CCR5 incubated for 6 to 8 hrs by luciferase reporter assay | Human immunodeficiency virus 1 | 1 | assay format | Scientific Literature | ||
| 8. | ALA4259333 | B | Inhibition of gp41 D36G mutant in T20-resistant HIV1 NL4-3 assessed as inhibition of viral infection in Ghost (3)X4/R5 cells after 48 hrs by Bright-Glo luciferase reporter gene assay | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4259334 | B | Inhibition of gp41 I37T mutant in T20-resistant HIV1 NL4-3 assessed as inhibition of viral infection in Ghost (3)X4/R5 cells after 48 hrs by Bright-Glo luciferase reporter gene assay | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4259335 | B | Inhibition of gp41 V38A mutant in T20-resistant HIV1 NL4-3 assessed as inhibition of viral infection in Ghost (3)X4/R5 cells after 48 hrs by Bright-Glo luciferase reporter gene assay | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4259336 | B | Inhibition of gp41 V38M mutant in T20-resistant HIV1 NL4-3 assessed as inhibition of viral infection in Ghost (3)X4/R5 cells after 48 hrs by Bright-Glo luciferase reporter gene assay | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4259337 | B | Inhibition of gp41 Q40H mutant in T20-resistant HIV1 NL4-3 assessed as inhibition of viral infection in Ghost (3)X4/R5 cells after 48 hrs by Bright-Glo luciferase reporter gene assay | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA4259338 | B | Inhibition of gp41 N43K mutant in T20-resistant HIV1 NL4-3 assessed as inhibition of viral infection in Ghost (3)X4/R5 cells after 48 hrs by Bright-Glo luciferase reporter gene assay | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4259339 | B | Inhibition of gp41 I37T/N43K double mutant in T20-resistant HIV1 NL4-3 assessed as inhibition of viral infection in Ghost (3)X4/R5 cells after 48 hrs by Bright-Glo luciferase reporter gene assay | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4259340 | B | Inhibition of gp41 G36S/V38M double mutant in T20-resistant HIV1 NL4-3 assessed as inhibition of viral infection in Ghost (3)X4/R5 cells after 48 hrs by Bright-Glo luciferase reporter gene assay | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4259341 | B | Inhibition of gp41 V38A/N42T double mutant in T20-resistant HIV1 NL4-3 assessed as inhibition of viral infection in Ghost (3)X4/R5 cells after 48 hrs by Bright-Glo luciferase reporter gene assay | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4265063 | B | Induction of conformational changes in HIV1 cYTA48P envelope glycoprotein gp120 infected in PM1/CCR5 cells assessed as mean fluorescence intensity using CD4i monoclonal antibody 4C11 at 100 uM after 15 mins by FACS analysis | Human immunodeficiency virus 1 | 36 | cell-based format | Scientific Literature | ||
| 18. | ALA4265064 | B | Induction of conformational changes in HIV1 cYTA48P envelope glycoprotein gp120 infected in PM1/CCR5 cells assessed as mean fluorescence intensity using CD4i monoclonal antibody 4C11 at 100 uM after 15 mins by FACS analysis relative to NBD-556 | Human immunodeficiency virus 1 | 16 | cell-based format | Scientific Literature | ||
| 19. | ALA4322096 | B | Inhibition of HIV1 JRFL gp120 assessed as reduction in CD4/gp 120 complex formation incubated for 1 hr by ELISA | Human immunodeficiency virus 1 | 4 | single protein format | Scientific Literature | ||
| 20. | ALA4322097 | B | Inhibition of HIV1 gp120 assessed as increase in anti-DNP binding to immobilized HIV-1 gp120 incubated for 1 hr by ELISA | Human immunodeficiency virus 1 | 2 | single protein format | Scientific Literature |
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